Lewis C. Cantley

Publishes on PI3K/AKT/mTOR signaling in cancer, Cancer, Hypoxia, and Metabolism, Protein Kinase Regulation and GTPase Signaling. 1.4k papers and 205.1k citations.

PubIndex Score98Top 2%How it's scored

🌟#4 Current Senior Leader in Metabolism, Diabetes, and Cancer 🌟#6 Current Senior Leader in PI3K/AKT/mTOR signaling in cancer 🌟#8 Current Senior Leader in FOXO transcription factor regulation 🌟#8 Current Senior Leader in Protein Kinase Regulation and GTPase Signaling

1.4kPublications

205.1kTotal Citations

#4in Metabolism, Diabetes, and Cancer

First publication: 1973First senior author: 1977

PI3K/AKT/mTOR signaling in cancer Cancer, Hypoxia, and Metabolism Protein Kinase Regulation and GTPase Signaling Metabolism, Diabetes, and Cancer RNA modifications and cancer

Top publicationsby citations

<i>MET</i> Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling

Jeffrey A. Engelman, Pasi A. Jänne, Kreshnik Zejnullahu et al.|Science|2007

Cited by 4.5k

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

Haoqiang Ying, Ronald A. DePinho, Alec C. Kimmelman et al.|Cell|2012

Cited by 2k

Chromosomal instability drives metastasis through a cytosolic DNA response

Samuel F. Bakhoum, Lewis C. Cantley|Nature|2018

Cited by 1.5k

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

Jeffrey A. Engelman, Kwok‐Kin Wong, Liang Chen et al.|Nature Medicine|2008

Cited by 1.3k

Signalling through the lipid products of phosphoinositide-3-OH kinase

Alex Toker, Lewis C. Cantley|Nature|1997

Cited by 1.3k