Leaderboards/Metabolism, Diabetes, and Cancer

Metabolism, Diabetes, and Cancer

Last updated June 1, 2026

Rising Stars

New and hot

Rising Stars Papers

Lysine l-lactylation is the dominant lactylation isomer induced by glycolysis

Nature Chemical Biology|2024

127 cit.

Lac-Phe mediates the effects of metformin on food intake and body weight

Nature Metabolism|2024

73 cit.

A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites

Cell|2024

56 cit.

mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism

Nature Communications|2024

44 cit.

Semaglutide Improves Liver Steatosis and De Novo Lipogenesis Markers in Obese and Type-2-Diabetic Mice with Metabolic-Dysfunction-Associated Steatotic Liver Disease

International Journal of Molecular Sciences|2024

37 cit.

Dynamic investigation of hypoxia-induced L-lactylation

Proceedings of the National Academy of Sciences|2025

32 cit.

AMPK and Beyond: The Signaling Network Controlling RabGAPs and Contraction-Mediated Glucose Uptake in Skeletal Muscle

International Journal of Molecular Sciences|2024

29 cit.

SGLT2 inhibitor promotes mitochondrial dysfunction and ER-phagy in colorectal cancer cells

Cellular & Molecular Biology Letters|2024

26 cit.

HIF1α-dependent uncoupling of glycolysis suppresses tumor cell proliferation

Cell Reports|2024

19 cit.

AMPK protects proximal tubular epithelial cells from lysosomal dysfunction and dedifferentiation induced by lipotoxicity

Autophagy|2024

15 cit.

Emerging Leaders

Gaining momentum

Emerging Leaders Researchers

Emerging Leaders Papers

Astrocytic GLUT1 deletion in adult mice enhances glucose metabolism and resilience to stroke

Nature Communications|2025

21 cit.

Anti-Inflammatory Properties of Eugenol in Lipopolysaccharide-Induced Macrophages and Its Role in Preventing β-Cell Dedifferentiation and Loss Induced by High Glucose-High Lipid Conditions

Molecules|2023

14 cit.

GUK1 activation is a metabolic liability in lung cancer

Cell|2025

13 cit.

The Effects of Psilocybin on Lipopolysaccharide-Induced Inflammation in THP-1 Human Macrophages

Psychoactives|2024

12 cit.

Synergistic targeting of cancer cells through simultaneous inhibition of key metabolic enzymes

Cell Death and Differentiation|2025

10 cit.

PKA plays a conserved role in regulating gene expression and metabolic adaptation by phosphorylating Rpd3/HDAC1

Nature Communications|2025

6 cit.

An alternative route for β-hydroxybutyrate metabolism supports cytosolic acetyl-CoA synthesis in cancer cells

Nature Metabolism|2025

6 cit.

Single and Combined Impact of Semaglutide, Tirzepatide, and Metformin on β-Cell Maintenance and Function Under High-Glucose–High-Lipid Conditions: A Comparative Study

International Journal of Molecular Sciences|2025

4 cit.

Mechanism and cellular actions of the potent AMPK inhibitor BAY-3827

Science Advances|2025

4 cit.

PPM1M, an LRRK2-counteracting, phosphoRab12-preferring phosphatase with a potential link to Parkinson’s disease

Cell Reports|2025

3 cit.

All-Time Leaders

The canon

All-Time Leaders Researchers

All-Time Leaders Papers

Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade

Journal of Biology|2003

1.6k cit.

Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease

Journal of Hepatology|2014

1.5k cit.

Metformin: From Mechanisms of Action to Therapies

Cell Metabolism|2014

1.5k cit.

Insulin Receptor Signaling in Normal and Insulin-Resistant States

Cold Spring Harbor Perspectives in Biology|2014

1.4k cit.

Effects of free fatty acids on glucose transport and IRS-1–associated phosphatidylinositol 3-kinase activity

Journal of Clinical Investigation|1999

1.3k cit.

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

Journal of Clinical Investigation|2010

1.2k cit.

The integrative biology of type 2 diabetes

Nature|2019

1.1k cit.

Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

Journal of Biological Chemistry|1999

1.1k cit.

The Anti-diabetic Drugs Rosiglitazone and Metformin Stimulate AMP-activated Protein Kinase through Distinct Signaling Pathways

Journal of Biological Chemistry|2002

1k cit.

Co-purification and Direct Interaction of Ras with Caveolin, an Integral Membrane Protein of Caveolae Microdomains

Journal of Biological Chemistry|1996

999 cit.

Reagents for Metabolism, Diabetes, and Cancer

Citation-validated products used in this field

🔥 Trending

Gaining adoption fast

⭐ Recommended

Best all-around

Cell Signaling Technology

MNDA (3C1) Rat Monoclonal Antibody

Cited in 28 papers

#3329$158

View Evidence →Cell Signaling Technology

Phospho-CDK5 (Tyr15) (E6C8N) Rabbit Monoclonal Antibody

Cited in 27 papers

#19051$181

View Evidence →Cell Signaling Technology

ApoA5 (2G1H11) Mouse Monoclonal Antibody

Cited in 26 papers

#3335$158

View Evidence →

🌟 All-Time

Most validated

Cell Signaling Technology

CD38 (E9F5A) Rabbit Monoclonal Antibody (Alexa Fluor® 647 Conjugate)

Cited in 48 papers

#27887$465

View Evidence →Cell Signaling Technology

GMPS Antibody

Cited in 44 papers

#14602$317

View Evidence →Cell Signaling Technology

BrdU (Bu20a) Mouse Monoclonal Antibody (PE Conjugate)

Cited in 35 papers

#50230$465

View Evidence →

Metabolism, Diabetes, and Cancer

Rising Stars

Rising Stars Researchers

Rising Stars Papers

Emerging Leaders

Emerging Leaders Researchers

Emerging Leaders Papers

All-Time Leaders

All-Time Leaders Researchers

All-Time Leaders Papers

Reagents for Metabolism, Diabetes, and Cancer

🔥 Trending

⭐ Recommended

🌟 All-Time