Leaderboards/FOXO transcription factor regulation

FOXO transcription factor regulation

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Jinghui Lei
Capital Medical University
2
Sufang Zhong
Peking University Shenzhen Hospital
3
Goda Snieckute
University of Copenhagen
4
Unbin Chae
Korea Research Institute of Bioscience and Biotechnology
5
Adrián Álvarez-Varela
Institute for Research in Biomedicine
6
Na Liu
Jiangsu University
7
Lisonia Gkioni
Max Planck Institute for Biology of Ageing
8
Asma’a H. Mohamed
Al-Furat Al-Awsat Technical University
9
Beiping Zhong
Second Affiliated Hospital of Guangzhou Medical University
10
Keun-Woo Lee
Samsung (South Korea)

Papers

1
Publication in Cell (2025) [53 citations, W4411276971]
Cell|2025
53 cit.
2
Publication in Oral Science and Homeostatic Medicine (2025) [1 citation, W4411831404]
Oral Science and Homeostatic Medicine|2025
1 cit.
3
Publication in Ageing and Cancer Research & Treatment (2026) [W7163339163]
Ageing and Cancer Research & Treatment|2026
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Gang Ren
Peking University Shougang Hospital
2
Spencer R. Rosario
Roswell Park Comprehensive Cancer Center
3
Stephanie Heinzlmeir
German Cancer Research Center
4
Guopei Zheng
Guangzhou Medical University Cancer Hospital
5
Christian G. Riedel
Karolinska Institutet
6
James V. Alvarez
Fred Hutch Cancer Center
7
Xiong Li
Nanjing University of Chinese Medicine
8
Jason M. Sheltzer
Yale University
9
Lei Liu
Affiliated Hospital of Jining Medical University
10
Maria J. Rodríguez Colman
University Medical Center Utrecht

Papers

1
Oncogene-like addiction to aneuploidy in human cancers
Science|2023
161 cit.
2
Genome-wide identification and analysis of prognostic features in human cancers
Cell Reports|2022
129 cit.
3
Extensive protein dosage compensation in aneuploid human cancers
Genome Research|2022
88 cit.
4
Lactate controls cancer stemness and plasticity through epigenetic regulation
Cell Metabolism|2025
78 cit.
5
Integrative multi-omics analysis uncovers tumor-immune-gut axis influencing immunotherapy outcomes in ovarian cancer
Nature Communications|2024
30 cit.
6
Single-cell transcriptional atlas of tumor-associated macrophages in breast cancer
Breast Cancer Research|2024
25 cit.
7
Inhibition of a lower potency target drives the anticancer activity of a clinical p38 inhibitor
Cell chemical biology|2023
24 cit.
8
Rewiring glucose metabolism improves 5-FU efficacy in p53-deficient/KRASG12D glycolytic colorectal tumors
Communications Biology|2022
21 cit.
9
Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis
Aging|2023
13 cit.
10
Metabolic Dysregulation Explains the Diverse Impacts of Obesity in Males and Females with Gastrointestinal Cancers
International Journal of Molecular Sciences|2023
11 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Domenico Accili
Columbia University
2
Boudewijn Burgering
University Medical Center Utrecht
3
Cynthia Kenyon
Buck Institute for Research on Aging
4
Gary Ruvkun
Harvard University
5
Michael E. Greenberg
Harvard University
6
Eric W.‐F. Lam
Ottawa Hospital
7
Morris F. White
Joslin Diabetes Center
8
Lewis C. Cantley
Harvard University
9
Michael F. Clarke
Stanford University
10
Akiyoshi Fukamizu
University of Tsukuba

Papers

1
Prospective identification of tumorigenic breast cancer cells
Proceedings of the National Academy of Sciences|2003
10.4k cit.
2
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
Cell|1999
6.6k cit.
3
Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery
Cell|1997
5.7k cit.
4
Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis
Science|1995
5.3k cit.
5
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
Nature|2000
5k cit.
6
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
Cell|1993
4.2k cit.
7
A C. elegans mutant that lives twice as long as wild type
Nature|1993
3.4k cit.
8
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
Science|2004
3.2k cit.
9
Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene
Nature|1984
3.2k cit.
10
Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells
Cancer Research|2006
3.1k cit.

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