Synthesis of 5,6-Dihydro-4-hydroxy-2- pyrones as HIV-1 Protease Inhibitors: The Profound Effect of Polarity on Antiviral ActivitySusan E. Hagen, Steven VanderRoest, J. V. N. Vara Prasad et al.|Journal of Medicinal Chemistry|1997Cited by 62
Nonpeptidic HIV protease inhibitors possessing excellent antiviral activities and therapeutic indices. PD 178390: a lead HIV protease inhibitorJagdish Prasad, John W. Erickson, Christine Humblet et al.|Bioorganic & Medicinal Chemistry|1999Cited by 17
Nonpeptidic HIV protease inhibitors: 6-alkyl-5, 6-dihydropyran-2-ones possessing achiral 3-(4-amino/carboxamide-2-t-butyl, 5-methylphenyl thio) moiety: Antiviral activities and pharmacokinetic propertiesJ. V. N. Vara Prasad, Joanne Brodfuehrer, Fred E. Boyer et al.|Bioorganic & Medicinal Chemistry Letters|1999Cited by 8
Nonpeptidic HIV Protease Inhibitors: 4-Hydroxy-pyran-2-one Inhibitors with Functional Tethers to P1Phenyl Ring to Reach S3Pocket of the EnzymeJ. V. N. Vara Prasad, John M. Domagala, Donna Ferguson et al.|Biochemical and Biophysical Research Communications|1996Cited by 6
Nonpeptidic HIV protease inhibitors: 6-alkyl-5,6-dihydropyran-2-ones possessing a novel and achiral 3-(2-t-butyl-5-methyl-4-sulfamate)phenylthio moietyJ. V. N. Vara Prasad, Michael Sinz, Larry J. Markoski et al.|Bioorganic & Medicinal Chemistry Letters|1999Cited by 4