Synthesis of 5,6-Dihydro-4-hydroxy-2- pyrones as HIV-1 Protease Inhibitors: The Profound Effect of Polarity on Antiviral ActivitySusan E. Hagen, Steven VanderRoest, J. V. N. Vara Prasad et al.|Journal of Medicinal Chemistry|1997Cited by 62
5,6-Dihydropyran-2-ones Possessing Various Sulfonyl Functionalities: Potent Nonpeptidic Inhibitors of HIV ProteaseF Boyer, John W. Erickson, J. V. N. Vara Prasad et al.|Journal of Medicinal Chemistry|2000Cited by 51
4-Hydroxy-5,6-dihydropyrones. 2. Potent Non-Peptide Inhibitors of HIV ProteaseBradley D. Tait, Beishan Liu, Susan E. Hagen et al.|Journal of Medicinal Chemistry|1997Cited by 49
A new class of anti-HIV-1 agents targeted toward the nucleocapsid protein NCp7: The 2,2′-dithiobisbenzamidesJohn M. Domagala, Robert Schultz, John P. Bader et al.|Bioorganic & Medicinal Chemistry|1997Cited by 42
HIV Protease Inhibitors Possessing a Novel, High-Affinity, and Achiral P1'/P2' Ligand with a Unique Pattern of in Vitro Resistance. Importance of a Conformationally-Restricted Template in the Design of Enzyme InhibitorsJ. V. N. Vara Prasad, John M. Domagala, Elizabeth A. Lunney et al.|Journal of the American Chemical Society|1995Cited by 30