Nonpeptidic HIV Protease Inhibitors: 4-Hydroxy-pyran-2-one Inhibitors with Functional Tethers to P1Phenyl Ring to Reach S3Pocket of the Enzyme
J. V. N. Vara Prasad(Pfizer (United States)), John M. Domagala(Pfizer (United States)), Steve Vander Roest(University of Michigan), Robert Guttendorf, Elizabeth A. Lunney(Pfizer (United States)), Eric L. Reyner, Andrea Heldsinger, Stephen J. Gracheck(Pfizer (United States)), James M. Saunders(Pfizer (United States)), Donna Ferguson(Pfizer (United States)), Barbra H. Stewart, Kimberly S. Para(Pfizer (United States)), Peter J. Tummino(Intarcia Therapeutics (United States)), Thomas J. McQuade(University of Massachusetts Chan Medical School)
Cited by 6
Related Papers
Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori
|Nature|1999|1.9k
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
|Nature|2012|1.8k
Hydrolysis of Biological Peptides by Human Angiotensin-converting Enzyme-related Carboxypeptidase
|Journal of Biological Chemistry|2002|1.4k
Residence Time of Receptor−Ligand Complexes and Its Effect on Biological Function
|Biochemistry|2008|550