Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19
Laura A. Vella(Children's Hospital of Philadelphia), Justin Kim, Mary M. Addison, Claudia P. Arevalo(University of Pennsylvania), Jennifer E. Wu(Parker Institute for Cancer Immunotherapy), Kevin O. McNerney(Children's Hospital of Philadelphia), Michael R. Betts(University of Pennsylvania), Sarah E. Henrickson(Children's Hospital of Philadelphia), Nicholas Han(Translational Therapeutics (United States)), Jessica H. Lee(Children's Hospital of Philadelphia), Aditi Chandra, Katelyn T. Byrne(Portland State University), David T. Teachey(Children's Hospital of Philadelphia), Sigrid Gouma(University of Pennsylvania), Scott E. Hensley(University of Pennsylvania), Hélène C. Descamps, Hamid Bassiri(Johnson & Johnson (United States)), Divij Mathew(Parker Institute for Cancer Immunotherapy), Yinghui Huang(Translational Therapeutics (United States)), Marcus J. Bolton(University of Pennsylvania), Nuala J. Meyer(Translational Therapeutics (United States)), Cécile Alanio(Inserm), Shane Kammerman, Derek A. Oldridge(California University of Pennsylvania), Julie Chase, E. John Wherry(Parker Institute for Cancer Immunotherapy), Sharon Adamski(United States Military Academy), Edward M. Behrens(Children's Hospital of Philadelphia), M. Betina Pampena(University of Pennsylvania), H.M. Giannini(Lung Institute), Caroline Diorio(Children's Hospital of Philadelphia), Josephine R. Giles(Parker Institute for Cancer Immunotherapy), Peyton Conrey(Children's Hospital of Philadelphia), Oliva Kuthuru(Translational Therapeutics (United States)), Amy E. Baxter(Translational Therapeutics (United States)), Alexander C. Huang(University of Pennsylvania), Cristina Jasen(Children's Hospital of Philadelphia), Elizabeth M. Anderson, Samir Sayed(Children's Hospital of Philadelphia), Leticia Kuri-Cervantes(University of Pennsylvania), Sokratis A. Apostolidis(University of Pennsylvania), Chakkapong Burudpakdee(Children's Hospital of Philadelphia), Kurt D’Andrea(University of Pennsylvania), Zahidul Alam, Zeyu Chen(Kingmed Diagnostics), André Ramos(Translational Therapeutics (United States)), Madison E. Weirick(University of Pennsylvania), Yaroslav Kaminskiy, Eileen C. Goodwin(University of Pennsylvania)
Cited by 206
Related Papers
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
|Nature|2010|1.8k
Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications
|Science|2020|1.7k