An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Teresa A. Soucy; Peter G. Smith; Michael A. Milhollen; Allison Berger; James M. Gavin; Sharmila Adhikari; James E. Brownell; Kristine Burke; David P. Cardin; Stephen Critchley; Courtney Cullis; Amanda Doucette; James Garnsey; Jeffrey Gaulin; Rachel E. Gershman; Anna R. Lublinsky; Alice McDonald; Hirotake Mizutani; Usha Narayanan; Edward J. Olhava; Stéphane Peluso; Mansoureh Rezaei; Michael D. Sintchak; Tina Talreja; Michael P. Thomas; Tary Traore; Štěpán Vyskočil; Gabriel S. Weatherhead; Jie Yu; Julie Zhang; Lawrence R. Dick; Christopher F. Claiborne; Mark Rolfe; Joseph B. Bolen; Steven Langston

doi:10.1038/nature07884

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Teresa A. Soucy(Millennium Engineering and Integration (United States)), Peter G. Smith(Millennium Engineering and Integration (United States)), Michael A. Milhollen(Millennium Engineering and Integration (United States)), Allison Berger(Millennium Engineering and Integration (United States)), James M. Gavin(Millennium Engineering and Integration (United States)), Sharmila Adhikari(Millennium Engineering and Integration (United States)), James E. Brownell(Millennium Engineering and Integration (United States)), Kristine Burke(Millennium Engineering and Integration (United States)), David P. Cardin(Millennium Engineering and Integration (United States)), Stephen Critchley(Millennium Engineering and Integration (United States)), Courtney Cullis(Millennium Engineering and Integration (United States)), Amanda Doucette(Millennium Engineering and Integration (United States)), James Garnsey(Millennium Engineering and Integration (United States)), Jeffrey Gaulin(Millennium Engineering and Integration (United States)), Rachel E. Gershman(Millennium Engineering and Integration (United States)), Anna R. Lublinsky(Millennium Engineering and Integration (United States)), Alice McDonald(Millennium Engineering and Integration (United States)), Hirotake Mizutani(Millennium Engineering and Integration (United States)), Usha Narayanan(Millennium Engineering and Integration (United States)), Edward J. Olhava(Millennium Engineering and Integration (United States)), Stéphane Peluso(Millennium Engineering and Integration (United States)), Mansoureh Rezaei(Millennium Engineering and Integration (United States)), Michael D. Sintchak(Millennium Engineering and Integration (United States)), Tina Talreja(Millennium Engineering and Integration (United States)), Michael P. Thomas(Millennium Engineering and Integration (United States)), Tary Traore(Millennium Engineering and Integration (United States)), Štěpán Vyskočil(Millennium Engineering and Integration (United States)), Gabriel S. Weatherhead(Millennium Engineering and Integration (United States)), Jie Yu(Millennium Engineering and Integration (United States)), Julie Zhang(Millennium Engineering and Integration (United States)), Lawrence R. Dick(Millennium Engineering and Integration (United States)), Christopher F. Claiborne(Millennium Engineering and Integration (United States)), Mark Rolfe(Millennium Engineering and Integration (United States)), Joseph B. Bolen(Millennium Engineering and Integration (United States)), Steven Langston(Millennium Engineering and Integration (United States))

Nature

April 1, 2009

10.1038/nature07884

Cited by 1,989

Abstract

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