Lawrence R. Dick

Biotechnology Institute

Publishes on Ubiquitin and proteasome pathways, Peptidase Inhibition and Analysis, Glycosylation and Glycoproteins Research. 71 papers and 11.2k citations.

71Publications

11.2kTotal Citations

Ubiquitin and proteasome pathways Peptidase Inhibition and Analysis Glycosylation and Glycoproteins Research Cancer-related Molecular Pathways Protein Degradation and Inhibitors

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Top publicationsby citations

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Kenneth L. Rock, Colette F. Gramm, Lisa Rothstein et al.|Cell|1994

Cited by 2.5k

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Teresa A. Soucy, Peter G. Smith, Michael A. Milhollen et al.|Nature|2009

Cited by 2k

Potent and selective inhibitors of the proteasome: Dipeptidyl boronic acids

Julian Adams, Mark L. Behnke, Shaowu Chen et al.|Bioorganic & Medicinal Chemistry Letters|1998

Cited by 683Open Access

Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets

Lynn Bedford, James Lowe, Lawrence R. Dick et al.|Nature Reviews Drug Discovery|2010

Cited by 556Open Access

Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ

James E. Brownell, Michael D. Sintchak, James M. Gavin et al.|Molecular Cell|2010

Cited by 461Open Access