The MIntAct project—IntAct as a common curation platform for 11 molecular interaction databases

Sandra Orchard(SIB Swiss Institute of Bioinformatics), Mais Ammari(University of Arizona), Bruno Aranda(European Bioinformatics Institute), Lionel Breuza(SIB Swiss Institute of Bioinformatics), Leonardo Briganti(University of Rome Tor Vergata), Fiona Broackes-Carter(Ontario Institute for Cancer Research), N. Campbell(UCL Australia), G.B. Chavali(Wellcome Trust), Carol Chen(University of British Columbia), Noemí del‐Toro(European Bioinformatics Institute), Margaret Duesbury(Wellcome Trust), Marine Dumousseau(European Bioinformatics Institute), Eugenia Galeota(University of Rome Tor Vergata), Ursula Hinz(University of Geneva), Marta Iannuccelli(University of Rome Tor Vergata), Sruthi Jagannathan(National University of Singapore), Rafael C. Jiménez(Wellcome Trust), Jyoti Khadake(Wellcome Trust), Astrid Lagreid(Norwegian University of Science and Technology), Luana Licata(University of Rome Tor Vergata), Ruth C. Lovering(UCL Australia), Birgit Meldal(Wellcome Trust), Anna N. Melidoni(University College London), Mila Milagros(Wellcome Trust), Daniele Peluso(Fondazione Santa Lucia), Livia Perfetto(University of Rome Tor Vergata), Pablo Porras(European Bioinformatics Institute), Arathi Raghunath(Community Connections), Sylvie Ricard‐Blum(Institut de Biologie et de Chimie des Protéines), Bernd Roechert(University of Geneva), André Stutz(SIB Swiss Institute of Bioinformatics), Michael Tognolli(University of Geneva), Kim Van Roey, Gianni Cesareni(University of Rome Tor Vergata), Henning Hermjakob(European Bioinformatics Institute)
Nucleic Acids Research
November 13, 2013
10.1093/nar/gkt1115
Cited by 1,953Open Access
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Abstract

IntAct (freely available at http://www.ebi.ac.uk/intact) is an open-source, open data molecular interaction database populated by data either curated from the literature or from direct data depositions. IntAct has developed a sophisticated web-based curation tool, capable of supporting both IMEx- and MIMIx-level curation. This tool is now utilized by multiple additional curation teams, all of whom annotate data directly into the IntAct database. Members of the IntAct team supply appropriate levels of training, perform quality control on entries and take responsibility for long-term data maintenance. Recently, the MINT and IntAct databases decided to merge their separate efforts to make optimal use of limited developer resources and maximize the curation output. All data manually curated by the MINT curators have been moved into the IntAct database at EMBL-EBI and are merged with the existing IntAct dataset. Both IntAct and MINT are active contributors to the IMEx consortium (http://www.imexconsortium.org).

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