Jieying Pan

Schwann cells locate at the leading edge of NI, can be induced by transforming growth factor β (TGF-β) signaling, promote tumor cell migration, and correlate with poor survival. We also identify basal-like and neural-reactive malignant subpopulations with distinct morphologies and heightened NI potential. This landscape depicting tumor-associated nerves highlights critical cancer-immune-neural interactions in situ and enlightens treatment development targeting NI.

Depth estimation is a critical enabling technology for sustainable intelligent transportation systems (ITSs), as it supports essential functions such as obstacle detection, navigation, and traffic management. However, existing Neural Radiance Field (NeRF)-based monocular depth estimation methods often suffer from high computational costs and poor performance in occluded regions, limiting their applicability in real-world, resource-constrained environments. To address these challenges, this paper proposes a lightweight monocular depth estimation framework that integrates a novel capacity redistribution strategy and an adaptive occlusion-aware training mechanism. By shifting computational load from resource-intensive multi-layer perceptrons (MLPs) to efficient separable convolutional encoder–decoder networks, our method significantly reduces memory usage to 234 MB while maintaining competitive accuracy. Furthermore, a divide-and-conquer training strategy explicitly handles occluded regions, improving reconstruction quality in complex urban scenarios. Experimental evaluations on the KITTI and V2X-Sim datasets demonstrate that our approach not only achieves superior depth estimation performance but also supports real-time operation on edge devices. This work contributes to the sustainable development of ITS by offering a practical, efficient, and scalable solution for environmental perception, with potential benefits for energy efficiency, system affordability, and large-scale deployment.

Monocular depth estimation is one of the key tasks in autonomous driving, which derives depth information of the scene from a single image. And it is a fundamental component for vehicle decision-making and perception. However, approaches currently face challenges such as visual artifacts, scale ambiguity and occlusion handling. These limitations lead to suboptimal performance in complex environments, reducing model efficiency and generalization and hindering their broader use in autonomous driving and other applications. To solve these challenges, this paper introduces a Neural Radiance Field (NeRF)-based monocular depth estimation method for autonomous driving. It introduces a Gaussian probability-based ray sampling strategy to effectively solve the problem of massive sampling points in large complex scenes and reduce computational costs. To improve generalization, a lightweight spherical network incorporating a fine-grained adaptive channel attention mechanism is designed to capture detailed pixel-level features. These features are subsequently mapped to 3D spatial sampling locations, resulting in diverse and expressive point representations for improving the generalizability of the NeRF model. Our approach exhibits remarkable performance on the KITTI benchmark, surpassing traditional methods in depth estimation tasks. This work contributes significant technical advancements for practical monocular depth estimation in autonomous driving applications.

Single cell analysis is essential for elucidating the contribution of rare cellular events or sub-populations in the onset and progression of disease pathology. Despite the importance of identifying cellular heterogeneity, most of the current understanding of disease is based on bulk population measurements. To address this need, recent advances in single cell technology and associated methods are gaining popularity and are resulting in the identification of critical features of disease.