Fred F. Kadlubar

National Center for Toxicological Research

Publishes on Carcinogens and Genotoxicity Assessment, Glutathione Transferases and Polymorphisms, Pharmacogenetics and Drug Metabolism. 353 papers and 21.6k citations.

PubIndex Score71Top 29% · seniorHow it's scored

353Publications

21.6kTotal Citations

First publication: 1968First senior author: 1973

Carcinogens and Genotoxicity Assessment Glutathione Transferases and Polymorphisms Pharmacogenetics and Drug Metabolism Genomics, phytochemicals, and oxidative stress Synthesis and Biological Evaluation

Top publicationsby citations

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.

Marguerite A. Butler, Fred F. Kadlubar, F. Peter Guengerich et al.|Proceedings of the National Academy of Sciences|1989

Cited by 638

Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites

Marguerite A. Butler, Fred F. Kadlubar, M. F. Lawsen et al.|Pharmacogenetics|1992

Cited by 418

Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps.

Nicholas P. Lang, Fred F. Kadlubar, Martin Hauer‐Jensen et al.|PubMed|1994

Cited by 392

Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon

Robert J. Turesky, Fred F. Kadlubar, Mary Ann Butler et al.|Carcinogenesis|1991

Cited by 342

Hepatic microsomal N-glucuronidation and nucleic acid binding of N-hydroxy arylamines in relation to urinary bladder carcinogenesis.

Fred F. Kadlubar, Elizabeth C. Miller, James A. Miller|PubMed|1977

Cited by 325