Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.Marguerite A. Butler, Fred F. Kadlubar, M. Iwasaki et al.|Proceedings of the National Academy of Sciences|1989Cited by 638
Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolitesMarguerite A. Butler, Fred F. Kadlubar, Neil E. Caporaso et al.|Pharmacogenetics|1992Cited by 418
Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps.Nicholas P. Lang, Fred F. Kadlubar, Martin Hauer‐Jensen et al.|PubMed|1994Cited by 392
SHORT COMMUNICATION: Genotype/phenotype discordance for human arylamine <i>N</i>-acetyltransferase (NAT2) reveals a new slow-acetylator allele common in African-AmericansDouglas A. Bell, George W. Lucier, Jack A. Taylor et al.|Carcinogenesis|1993Cited by 292
Polymorphisms for aromatic amine metabolism in humans: relevance for human carcinogenesis.Fred F. Kadlubar, Nicholas P. Lang, Keith R. Kaderlik et al.|Environmental Health Perspectives|1992Cited by 230