David M. Sabatini

Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

Publishes on PI3K/AKT/mTOR signaling in cancer, Protein Kinase Regulation and GTPase Signaling, CRISPR and Genetic Engineering. 532 papers and 156.3k citations.

PubIndex Score98Top 2%How it's scored

🌟#1 Current Senior Leader in PI3K/AKT/mTOR signaling in cancer 🌟#1 Current Senior Leader in Polyamine Metabolism and Applications 🌟#2 Current Senior Leader in Protein Kinase Regulation and GTPase Signaling 🌟#6 Current Senior Leader in Beetle Biology and Toxicology Studies 🌟#8 Current Senior Leader in Coagulation, Bradykinin, Polyphosphates, and Angioedema

532Publications

156.3kTotal Citations

#1in PI3K/AKT/mTOR signaling in cancer

First publication: 1958First senior author: 1958

PI3K/AKT/mTOR signaling in cancer Protein Kinase Regulation and GTPase Signaling CRISPR and Genetic Engineering Cancer, Hypoxia, and Metabolism Polyamine Metabolism and Applications

Top publicationsby citations

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

David A. Barbie, William C. Hahn, Etienne Meylan et al.|Nature|2009

Cited by 4.2k

mTOR signaling at a glance

Mathieu Laplante, David M. Sabatini|Journal of Cell Science|2009

Cited by 2.1k

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

Richard Possemato, David M. Sabatini|Nature|2011

Cited by 1.7k

Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase

Jason R. Cantor, David M. Sabatini, Caroline A. Lewis et al.|Cell|2017

Cited by 661

Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival

Alejo Efeyan, David M. Sabatini|Nature|2012

Cited by 450