An update on lipophilic efficiency as an important metric in drug design
Rebecca A. Gallego(Pfizer (United States)), T. Patrick Montgomery(Pfizer (United States)), Martin P. Edwards(Pfizer (United States))
Cited by 8
Related Papers
Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK)
|Journal of Medicinal Chemistry|2011|924
Using the Golden Triangle to optimize clearance and oral absorption
|Bioorganic & Medicinal Chemistry Letters|2009|382
Lipophilic Efficiency as an Important Metric in Drug Design
|Journal of Medicinal Chemistry|2018|340
Rapid assessment of a novel series of selective CB2 agonists using parallel synthesis protocols: A Lipophilic Efficiency (LipE) analysis
|Bioorganic & Medicinal Chemistry Letters|2009|269