Design and synthesis of pyrrolo[3,2-d]pyrimidine HER2/EGFR dual inhibitors: Improvement of the physicochemical and pharmacokinetic profiles for potent in vivo anti-tumor efficacy
Youichi Kawakita(Takeda (Japan)), Tomoyasu Ishikawa(Takeda (Japan)), Tadashi Yusa(Takeda (Japan)), Hiroshi Banno(Fujisawa City Hospital), Yukihiro Ikeda(Takeda (Japan)), Toshiya Tamura(Takeda (Japan)), Hiroshi Miki(Takeda (Japan)), Hidenori Kamiguchi(Takeda (Japan)), Yoshikazu Ohta(University of Miyazaki), Masaki Seto(Takeda (Japan)), Kazuhiro Miwa(Takeda (Japan)), Keiji Kamiyama(Takeda (Japan)), Toshimasa Tanaka(Takeda (Japan))
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