Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer
Tomohiro Kaku(Takeda (Japan)), Akihiro Tasaka(Takeda (Japan)), Takenori Hitaka(Takeda (Japan)), Akio Ojida(Kyushu University), Masami Kusaka(Takeda (Japan)), Nobuyuki Matsunaga(Takeda (Japan)), Takahito Hara(Takeda (Japan)), Teruaki Okuda(Takeda (Japan)), Satoru Asahi(Takeda (Japan)), Shuichi Furuya(Okayama University), Toshimasa Tanaka(Takeda (Japan)), Masuo Yamaoka, Mari Adachi(Takeda (Japan))
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