Design and Synthesis of Novel Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors Bearing a Pyrrolo[3,2-<i>d</i>]pyrimidine ScaffoldTomoyasu Ishikawa, Keiji Kamiyama, Noriyuki Habuka et al.|Journal of Medicinal Chemistry|2011Cited by 223
Structure-Based Approach for the Discovery of Pyrrolo[3,2-<i>d</i>]pyrimidine-Based EGFR T790M/L858R Mutant InhibitorsSatoshi Sogabe, Tomoyasu Ishikawa, Youichi Kawakita et al.|ACS Medicinal Chemistry Letters|2012Cited by 171
Design and synthesis of novel pyrimido[4,5-b]azepine derivatives as HER2/EGFR dual inhibitorsYouichi Kawakita, Tomoyasu Ishikawa, Masaki Seto et al.|Bioorganic & Medicinal Chemistry|2013Cited by 79
Design and Synthesis of Pyrrolo[3,2-<i>d</i>]pyrimidine Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors: Exploration of Novel Back-Pocket BindersYouichi Kawakita, Tomoyasu Ishikawa, Hiroshi Banno et al.|Journal of Medicinal Chemistry|2012Cited by 44
Design and synthesis of pyrrolo[3,2-d]pyrimidine HER2/EGFR dual inhibitors: Improvement of the physicochemical and pharmacokinetic profiles for potent in vivo anti-tumor efficacyYouichi Kawakita, Tomoyasu Ishikawa, Kazuhiro Miwa et al.|Bioorganic & Medicinal Chemistry|2012Cited by 29