Formation and persistence of arylamine DNA adducts in vivo.

Frederick A. Beland(National Center for Toxicological Research), Fred F. Kadlubar(National Center for Toxicological Research)

Environmental Health Perspectives

October 1, 1985

10.1289/ehp.856219

Cited by 220

Related Papers

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.

|Proceedings of the National Academy of Sciences|1989|638

Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites

|Pharmacogenetics|1992|418

Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps.

|PubMed|1994|392

Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon

|Carcinogenesis|1991|342

Hepatic microsomal N-glucuronidation and nucleic acid binding of N-hydroxy arylamines in relation to urinary bladder carcinogenesis.

|PubMed|1977|325