Detoxification of electrophilic compounds by glutathione S‐transferase catalysis: Determinants of individual response to chemical carcinogens and chemotherapeutic drugs?
Brian Coles(National Center for Toxicological Research), Fred F. Kadlubar(Courtauld Institute of Art)
Cited by 226
Related Papers
Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.
|Proceedings of the National Academy of Sciences|1989|638
Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites
|Pharmacogenetics|1992|418
Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon
|Carcinogenesis|1991|342