Leaderboards/Ubiquitin and proteasome pathways

Ubiquitin and proteasome pathways

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Tomer Tsaban
Hebrew University of Jerusalem
2
Stella Victorelli
Mayo Clinic
3
Xupeng Yang
Ministry of Education
4
Shahin Ramazi
Tarbiat Modares University
5
Nathaniel J. Henning
Berkeley College
6
Green Ahn
University of Washington
7
Ping Lai
Institute of Oncology Research
8
Adam D. Cotton
University of California, San Francisco
9
Christy Hong
University Medical Center Groningen
10
Oliver Hsia
University of Dundee

Papers

1
Precision treatment in advanced hepatocellular carcinoma
Cancer Cell|2024
393 cit.
2
Publication in Nature (2024) [181 citations, W4391994105]
Nature|2024
181 cit.
3
Publication in Immunity (2025) [101 citations, W4409254393]
Immunity|2025
101 cit.
4
Mitochondrial RNA cytosolic leakage drives the SASP
Nature Communications|2025
12 cit.
5
Study of photocatalytic degradation of dyeing wastewater with CdS nanoparticles anchored on cotton short staple-based carbon aerogels
Journal of Alloys and Compounds|2024
10 cit.
6
Abstract 6598: Inhibition of cGAS as a strategy to restore anti-tumor immunity response to STING agonist in chromosomally unstable tumors
Cancer Research|2024
0 cit.
7
Single-cell mapping of cholesterol metabolism reveals FDPS as a therapeutic vulnerability in hepatocellular carcinoma
Cellular Oncology|2026
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Eric S. Fischer
Dana-Farber Cancer Institute
2
Spencer R. Rosario
Roswell Park Comprehensive Cancer Center
3
Daniel A. Bachovchin
Memorial Sloan Kettering Cancer Center
4
Nir London
Weizmann Institute of Science
5
Deepak Nijhawan
Southwestern Medical Center
6
Nicholas Gaskill
The University of Texas Southwestern Medical Center
7
Maria Goralski
The University of Texas Southwestern Medical Center
8
Kanyi Pu
Nanyang Technological University
9
Ingrid E. Wertz
Pliant (United States)
10
Xiaobao Yang
Beijing Friendship Hospital

Papers

1
Nanoparticles with ultrasound-induced afterglow luminescence for tumour-specific theranostics
Nature Biomedical Engineering|2022
252 cit.
2
Molecular radio afterglow probes for cancer radiodynamic theranostics
Nature Materials|2023
190 cit.
3
Renal clearable polyfluorophore nanosensors for early diagnosis of cancer and allograft rejection
Nature Materials|2022
189 cit.
4
A Dual‐Locked Activatable Phototheranostic Probe for Biomarker‐Regulated Photodynamic and Photothermal Cancer Therapy
Angewandte Chemie International Edition|2022
169 cit.
5
Activatable near-infrared probes for the detection of specific populations of tumour-infiltrating leukocytes in vivo and in urine
Nature Biomedical Engineering|2023
157 cit.
6
Catalytical nano-immunocomplexes for remote-controlled sono-metabolic checkpoint trimodal cancer therapy
Nature Communications|2022
139 cit.
7
Activatable Cancer Sono‐Immunotherapy using Semiconducting Polymer Nanobodies
Advanced Materials|2022
132 cit.
8
Checkpoint Nano‐PROTACs for Activatable Cancer Photo‐Immunotherapy
Advanced Materials|2022
116 cit.
9
A Dual‐Locked Tandem Fluorescent Probe for Imaging of Pyroptosis in Cancer Chemo‐Immunotherapy
Advanced Materials|2022
100 cit.
10
Chemiluminescent Probes with Long‐Lasting High Brightness for In Vivo Imaging of Neutrophils
Angewandte Chemie International Edition|2022
92 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Alfred L. Goldberg
Harvard University
2
Alexander Varshavsky
California Institute of Technology
3
Raymond J. Deshaies
Howard Hughes Medical Institute
4
J. Wade Harper
Harvard Stem Cell Institute
5
Stephen J. Elledge
Howard Hughes Medical Institute
6
Kenneth C. Anderson
Dana-Farber Cancer Institute
7
Marc W. Kirschner
Harvard University
8
Craig M. Crews
Yale University
9
David Beach
Hitachi (Japan)
10
Keiji Tanaka
Tokyo Metropolitan Institute of Medical Science

Papers

1
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
Cell|1993
5.7k cit.
2
Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells
Cell|2015
3.7k cit.
3
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
Nature|1993
3.7k cit.
4
p21 is a universal inhibitor of cyclin kinases
Nature|1993
3.4k cit.
5
Dynamic instability of microtubule growth
Nature|1984
3.4k cit.
6
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
Science|2007
3.1k cit.
7
A protein factor essential for microtubule assembly.
Proceedings of the National Academy of Sciences|1975
3.1k cit.
8
Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy
Cell|2004
3k cit.
9
Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes
Science|2003
2.7k cit.
10
A Phase 2 Study of Bortezomib in Relapsed, Refractory Myeloma
New England Journal of Medicine|2003
2.6k cit.

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