Cell Signaling Technology

BRD4 (E2A7X) Rabbit Monoclonal Antibody

#13440 · $174,866

70
Evidence Score · Well-Established
Used by 125 independent labs across 144 papers. How we score this →
100
Citing papers
3.6k
Combined citations
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Research areas

Protein Degradation and Inhibitors47Ubiquitin and proteasome pathways25Histone Deacetylase Inhibitors Research21Peptidase Inhibition and Analysis9Chromatin Remodeling and Cancer8Multiple Myeloma Research and Treatments8Cancer-related gene regulation7Epigenetics and DNA Methylation7

Papers citing this product

1
PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer
Proceedings of the National Academy of Sciences·2016·825 cit.·DOI
2
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
Nature Medicine·2015·414 cit.·DOI
3
Suppression of BRD4 inhibits human hepatocellular carcinoma by repressing MYC and enhancing BIM expression
Oncotarget·2015·117 cit.·DOI
4
Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer
Nature Communications·2021·115 cit.·DOI
5
Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism
Nature Communications·2022·109 cit.·DOI
6
The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity
Cancer Cell·2023·93 cit.·DOI
7
Epigenomic landscape and 3D genome structure in pediatric high-grade glioma
Science Advances·2021·91 cit.·DOI
8
Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV
Journal of Clinical Investigation·2019·84 cit.·DOI
9
Chem-map profiles drug binding to chromatin in cells
Nature Biotechnology·2023·68 cit.·DOI
10
Hypoxia deactivates epigenetic feedbacks via enzyme-derived clicking proteolysis-targeting chimeras
Science Advances·2022·67 cit.·DOI

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