Leaderboards/RNA Research and Splicing

RNA Research and Splicing

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Eliza Yankova
Wellcome/MRC Cambridge Stem Cell Institute
2
Carmen Bravo González‐Blas
VIB-KU Leuven Center for Brain & Disease Research
3
Ibraheem Alshareedah
Howard Hughes Medical Institute
4
Pietro Boccaletto
International Institute of Molecular and Cell Biology
5
Joseph Nasser
Harvard University
6
Marc Elosua-Bayés
Centro Nacional de Análisis Genómico
7
X. Rosa
Lucile Packard Children's Hospital
8
Heankel Lyons
The University of Texas Southwestern Medical Center
9
Fuliang Xie
Chongqing University
10
Andrea Cappannini
International Institute of Molecular and Cell Biology

Papers

1
Sequence-specific interactions determine viscoelasticity and ageing dynamics of protein condensates
Nature Physics|2024
146 cit.
2
Determinants of viscoelasticity and flow activation energy in biomolecular condensates
Science Advances|2024
84 cit.
3
Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation
Nature Cell Biology|2024
75 cit.
4
Publication in Cell (2025) [21 citations, W4409801542]
Cell|2025
21 cit.
5
The human RAD52 complex undergoes phase separation and facilitates bundling and end-to-end tethering of RAD51 presynaptic filaments
Nucleic Acids Research|2026
3 cit.
6
Abstract 1768: Pharmacological inhibition of METTL1 as a novel therapeutic strategy against aggressive malignancies
Cancer Research|2025
0 cit.
7
Publication in Lab on a Chip (2026) [W7135045376]
Lab on a Chip|2026
0 cit.
8
Publication in BJC Reports (2026) [W7160080824]
BJC Reports|2026
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Kyle Kai‐How Farh
Illumina (United States)
2
Alessandra Dall’Agnese
Whitehead Institute for Biomedical Research
3
Fengxiang Wei
Shantou University
4
Alex S. Holehouse
Washington University in St. Louis
5
Smita Krishnaswamy
Yale University
6
J Engreitz
Broad Institute
7
Kathy S. Lin
Howard Hughes Medical Institute
8
Abed AlFatah Mansour
Salk Institute for Biological Studies
9
Jan-Hendrik Spille
University of Illinois Chicago
10
Elzo de Wit
The Netherlands Cancer Institute

Papers

1
Direct prediction of intrinsically disordered protein conformational properties from sequence
Nature Methods|2024
226 cit.
2
The landscape of tolerated genetic variation in humans and primates
Science|2023
177 cit.
3
Compatibility rules of human enhancer and promoter sequences
Nature|2022
167 cit.
4
Identification of constrained sequence elements across 239 primate genomes
Nature|2023
113 cit.
5
Convergence of coronary artery disease genes onto endothelial cell programs
Nature|2024
108 cit.
6
Multiscale PHATE identifies multimodal signatures of COVID-19
Nature Biotechnology|2022
80 cit.
7
Sequence-based prediction of intermolecular interactions driven by disordered regions
Science|2025
77 cit.
8
Rare penetrant mutations confer severe risk of common diseases
Science|2023
75 cit.
9
Transformer-based protein generation with regularized latent space optimization
Nature Machine Intelligence|2022
71 cit.
10
An Introduction to the Stickers-and-Spacers Framework as Applied to Biomolecular Condensates
Methods in molecular biology|2022
70 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Thomas D. Schmittgen
University of Florida
2
Simon Anders
European Molecular Biology Laboratory
3
David P. Bartel
Howard Hughes Medical Institute
4
Gordon K. Smyth
The University of Melbourne
5
Lior Pachter
California Institute of Technology
6
Thomas Tuschl
Howard Hughes Medical Institute
7
Gideon Dreyfuss
University of Pennsylvania
8
Robert Tjian
University of California, Berkeley
9
Roy Parker
Howard Hughes Medical Institute
10
Chuan He
University of Chicago

Papers

1
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
Methods|2001
181.5k cit.
2
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Genome biology|2014
100.5k cit.
3
<tt>edgeR</tt> : a Bioconductor package for differential expression analysis of digital gene expression data
Bioinformatics|2009
44.5k cit.
4
limma powers differential expression analyses for RNA-sequencing and microarray studies
Nucleic Acids Research|2015
43k cit.
5
Analyzing real-time PCR data by the comparative CT method
Nature Protocols|2008
26.7k cit.
6
HTSeq—a Python framework to work with high-throughput sequencing data
Bioinformatics|2014
22.7k cit.
7
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
Nature Biotechnology|2010
16.5k cit.
8
Differential expression analysis for sequence count data
Genome biology|2010
16.4k cit.
9
Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
Nature Protocols|2012
12.9k cit.
10
Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments
Statistical Applications in Genetics and Molecular Biology|2004
12k cit.

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