Leaderboards/Pancreatic function and diabetes

Pancreatic function and diabetes

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Diego Balboa
University of Helsinki
2
Chien-Ting Wu
The University of Texas Southwestern Medical Center
3
Adam Ramzy
University of British Columbia
4
Mengshu Jia
East China University of Science and Technology
5
Lasse Maretty
Novo Nordisk (Denmark)
6
Nazma Malik
MRC London Institute of Medical Sciences
7
Lianggong Ding
Nutrition Sciences (Belgium)
8
Kimberley El
Duke Medical Center
9
Daniel J. Puleston
Bloomberg (United States)
10
Tongyue Yang
First Affiliated Hospital of Zhengzhou University

Papers

1
An update on chronic complications of diabetes mellitus: from molecular mechanisms to therapeutic strategies with a focus on metabolic memory
Molecular Medicine|2024
103 cit.
2
Publication in Nature Medicine (2025) [66 citations, W4406051813]
Nature Medicine|2025
66 cit.
3
Glucose controls lipolysis through Golgi PtdIns4P-mediated regulation of ATGL
Nature Cell Biology|2024
32 cit.
4
Associations between life’s essential 8 and metabolic health among us adults: insights of NHANES from 2005 to 2018
Acta Diabetologica|2024
9 cit.
5
The role of metabolic memory in diabetic kidney disease: identification of key genes and therapeutic targets
Frontiers in Pharmacology|2024
3 cit.
6
The role of reactive oxygen species in oxidative-induced neoplastic transformation
PEARL (University of Plymouth)|2024
0 cit.
7
Cardiac autonomic neuropathy is associated with the incidence and progression of cardiovascular–kidney–metabolic syndrome
European Journal of Preventive Cardiology|2026
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Jeffrey R. Millman
Washington University in St. Louis
2
Costas A. Lyssiotis
University of Michigan
3
Meritxell Huch
Center for Systems Biology Dresden
4
Hai‐long Piao
Dalian Institute of Chemical Physics
5
Alejandra Tomás
Imperial College London
6
Jonathan E. Campbell
Duke University
7
Cheng‐Ran Xu
Peking University
8
Changtao Jiang
Peking University
9
Dana Avrahami
Hebrew University of Jerusalem
10
Chen‐Song Zhang
Xiamen University

Papers

1
Gut symbionts alleviate MASH through a secondary bile acid biosynthetic pathway
Cell|2024
275 cit.
2
Gut bacteria alleviate smoking-related NASH by degrading gut nicotine
Nature|2022
211 cit.
3
USP22 regulates lipidome accumulation by stabilizing PPARγ in hepatocellular carcinoma
Nature Communications|2022
178 cit.
4
Microbial-host-isozyme analyses reveal microbial DPP4 as a potential antidiabetic target
Science|2023
166 cit.
5
Uridine-derived ribose fuels glucose-restricted pancreatic cancer
Nature|2023
149 cit.
6
Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context
eLife|2022
120 cit.
7
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets
Nature Metabolism|2023
112 cit.
8
OXPHOS promotes apoptotic resistance and cellular persistence in T <sub>H</sub> 17 cells in the periphery and tumor microenvironment
Science Immunology|2022
108 cit.
9
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK
Nature Metabolism|2022
96 cit.
10
Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification
Nature Cell Biology|2023
86 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Douglas A. Melton
Harvard Stem Cell Institute
2
Jeffrey M. Friedman
Rockefeller University
3
Hans Clevers
Hubrecht Institute for Developmental Biology and Stem Cell Research
4
Andrew T. Hattersley
University of Exeter
5
Peter C. Butler
University of California, Los Angeles
6
Gerald I. Shulman
Howard Hughes Medical Institute
7
C. Ronald Kahn
Joslin Diabetes Center
8
D. Grahame Hardie
University of Dundee
9
Claes B. Wollheim
University of Geneva
10
Randal J. Kaufman
Discovery Institute

Papers

1
Positional cloning of the mouse obese gene and its human homologue
Nature|1994
13.4k cit.
2
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
Nature|2009
7.2k cit.
3
Efficient<i>in vitro</i>synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter
Nucleic Acids Research|1984
6.4k cit.
4
Identification of stem cells in small intestine and colon by marker gene Lgr5
Nature|2007
5.7k cit.
5
Weight-Reducing Effects of the Plasma Protein Encoded by the <i>obese</i> Gene
Science|1995
4.5k cit.
6
β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes
Diabetes|2003
4k cit.
7
Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
Gastroenterology|2011
3.8k cit.
8
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
Nature Medicine|1995
3.7k cit.
9
Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC <sup>−/−</sup> Colon Carcinoma
Science|1997
3.3k cit.
10
THE MAMMALIAN UNFOLDED PROTEIN RESPONSE
Annual Review of Biochemistry|2005
3k cit.

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