Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato(Hubrecht Institute for Developmental Biology and Stem Cell Research), Robert G.J. Vries(University Medical Center Utrecht), Hugo J.G. Snippert(University Medical Center Utrecht), Marc van de Wetering(University Medical Center Utrecht), Nick Barker(Hubrecht Institute for Developmental Biology and Stem Cell Research), Daniel E. Stange(University Medical Center Utrecht), Johan H. van Es(University Medical Center Utrecht), Arie Abo(UNAVCO), Pekka Kujala(The Netherlands Cancer Institute), Peter J. Peters(The Netherlands Cancer Institute), Hans Clevers(Hubrecht Institute for Developmental Biology and Stem Cell Research)
Nature
March 29, 2009
Cited by 7,108

Abstract


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