Leaderboards/Gene Regulatory Network Analysis

Gene Regulatory Network Analysis

Last updated July 15, 2026

Rising Stars

Fresh ink, massive impact

Researchers

1
Dylan Cable
University of Michigan
2
Chenling Xu
Triple Ring Technologies (United States)
3
Sophia Müller‐Dott
Heidelberg University
4
Tal Ashuach
University of California, Berkeley
5
Yusuf Roohani
Stanford University
6
Constantin Ahlmann-Eltze
University College London
7
Jason Yang
California Institute of Technology
8
Stefan Peidli
Humboldt-Universität zu Berlin
9
Franz-Georg Wieland
University of Freiburg
10
David Hausmann
German Cancer Research Center

Papers

1
Publication in Nature Methods (2025) [95 citations, W4412929241]
Nature Methods|2025
95 cit.
2
Publication in Nature Communications (2025) [81 citations, W4406425222]
Nature Communications|2025
81 cit.
3
Virtual Cell Challenge: Toward a Turing test for the virtual cell
Cell|2025
59 cit.
4
Comprehensive evaluation of phosphoproteomic-based kinase activity inference
Nature Communications|2025
13 cit.
5
Publication in Nature Genetics (2025) [11 citations, W4406036487]
Nature Genetics|2025
11 cit.
6
Publication in RNA (2026) [1 citation, W7119551770]
RNA|2026
1 cit.
7
Publication in Neuro-Oncology (2025) [W4414800024]
Neuro-Oncology|2025
0 cit.

Emerging Leaders

Drafting the new consensus

Researchers

1
Smita Krishnaswamy
Yale University
2
Guoji Guo
Zhejiang University
3
Elizabeth N. Koch
University of Minnesota
4
Benjamin VanderSluis
University of Minnesota
5
Evan Z. Macosko
Broad Institute
6
Fei Chen
Broad Institute
7
Darren A. Cusanovich
University of Arizona
8
Michael A. Skinnider
Princeton University
9
Mehrtash Babadi
Broad Institute
10
Samantha A. Morris
Brigham and Women's Hospital

Papers

1
Unsupervised removal of systematic background noise from droplet-based single-cell experiments using CellBender
Nature Methods|2023
813 cit.
2
Dissecting cell identity via network inference and in silico gene perturbation
Nature|2023
647 cit.
3
Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease
Nature Neuroscience|2022
563 cit.
4
Early Alzheimer’s disease pathology in human cortex involves transient cell states
Cell|2023
208 cit.
5
Slide-tags enables single-nucleus barcoding for multimodal spatial genomics
Nature|2023
198 cit.
6
The molecular cytoarchitecture of the adult mouse brain
Nature|2023
183 cit.
7
Cell type-specific inference of differential expression in spatial transcriptomics
Nature Methods|2022
171 cit.
8
Spatial maps of T cell receptors and transcriptomes reveal distinct immune niches and interactions in the adaptive immune response
Immunity|2022
138 cit.
9
GATK-gCNV enables the discovery of rare copy number variants from exome sequencing data
Nature Genetics|2023
117 cit.
10
Systematic identification of cell-fate regulatory programs using a single-cell atlas of mouse development
Nature Genetics|2022
103 cit.

Current Senior Leaders

Wrote the book, still writing it

Researchers

1
Trey Ideker
Moores Cancer Center
2
Steven H. Strogatz
Cornell University
3
Uri Alon
Weizmann Institute of Science
4
Bernhard Ø. Palsson
University of California San Diego
5
Fabian J. Theis
Helmholtz Zentrum München
6
James J. Collins
Broad Institute
7
Stanislas Leibler
Institute for Advanced Study
8
Alexander van Oudenaarden
Royal Netherlands Academy of Arts and Sciences
9
Albert-Ĺaszló Barabási
Brigham and Women's Hospital
10
Peter S. Swain
Rockefeller University

Papers

1
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
Genome Research|2003
54.3k cit.
2
Collective dynamics of ‘small-world’ networks
Nature|1998
43.2k cit.
3
Emergence of Scaling in Random Networks
Science|1999
36.4k cit.
4
Statistical mechanics of complex networks
Reviews of Modern Physics|2002
20.6k cit.
5
SCANPY: large-scale single-cell gene expression data analysis
Genome biology|2018
9.3k cit.
6
Network Motifs: Simple Building Blocks of Complex Networks
Science|2002
7.5k cit.
7
Understanding individual human mobility patterns
Nature|2008
6.1k cit.
8
Stochastic Gene Expression in a Single Cell
Science|2002
5.7k cit.
9
Cytoscape 2.8: new features for data integration and network visualization
Bioinformatics|2010
5k cit.
10
A synthetic oscillatory network of transcriptional regulators
Nature|2000
4.8k cit.

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