Begacestat (GSI-953): A Novel, Selective Thiophene Sulfonamide Inhibitor of Amyloid Precursor Protein γ-Secretase for the Treatment of Alzheimer’s DiseaseRobert Martone, J. Steven Jacobsen, Scott C. Mayer et al.|Journal of Pharmacology and Experimental Therapeutics|2009Cited by 157
Discovery of Begacestat, a Notch-1-Sparing γ-Secretase Inhibitor for the Treatment of Alzheimer’s DiseaseScott C. Mayer, J. Steven Jacobsen, Anthony F. Kreft et al.|Journal of Medicinal Chemistry|2008Cited by 111
(S)-N-(5-Chlorothiophene-2-sulfonyl)-β,β-diethylalaninol a Notch-1-sparing γ-secretase inhibitorDerek C. Cole, J. Steven Jacobsen, Joseph R. Stock et al.|Bioorganic & Medicinal Chemistry Letters|2008Cited by 19
O3‐06‐07: GSI‐953 is a potent APP‐selective gamma‐secretase inhibitor for the treatment of Alzheimer's diseaseSteven J. Jacobsen, Robert Martone, Thomas A. Comery et al.|Alzheimer s & Dementia|2009Cited by 12
P4–244: Discovery of a novel series of notch–sparing γ–secretase inhibitorsBoyd L. Harrison, Steven J. Jacobsen, Anthony F. Kreft et al.|Alzheimer s & Dementia|2006Cited by 0