Shay Keren

An optimized noninvasive Raman microscope was used to evaluate tumor targeting and localization of single walled carbon nanotubes (SWNTs) in mice. Raman images were acquired in two groups of tumor-bearing mice. The control group received plain-SWNTs, whereas the experimental group received tumor targeting RGD-SWNTs intravenously. Raman imaging commenced over the next 72 h and revealed increased accumulation of RGD-SWNTs in tumor ( p < 0.05) as opposed to plain-SWNTs. These results support the development of a new preclinical Raman imager.

We demonstrate an innovative method for a real-time interrogation of fiber Bragg gratings based on low-coherence spectral interferometry of noiselike pulses. By analyzing the spectral interference at the output of a Michelson interferometer we obtained the impulse response of the grating with a time resolution of ~350 fs . Using the Gabor transformation, we could directly detect nonuniform regions inside the grating and could measure the spatial dependence of the resonance wavelength along the grating.

We demonstrate optical data storage in optical fibers and reconstruction by use of low-coherence spectral interferometry. The information was stored by means of writing fiber Bragg gratings with different central wavelengths at different locations of the fiber. We need only a single short pulse is needed to read all the stored data. The maximum theoretical reconstruction rate that can be obtained with our technique is 10 Tbits/s. Our storage technique can be useful for identifying users in optical communication networks.

We demonstrate a new method for measuring changes in temperature distribution caused by coupling a high-power laser beam into an optical fiber and by splicing two fibers. The measurement technique is based on interrogating a fiber Bragg grating by using low-coherence spectral interferometry. A large temperature change is found owing to coupling of a high-power laser into a multimode fiber and to splicing of two multimode fibers. Measurement of the temperature profile rather than the average temperature along the grating allows study of the cause of fiber heating. The new measurement technique enables us to monitor in real time the temperature profile in a fiber without the affecting system operation, and it might be important for developing and improving the reliability of high-power fiber components.