Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanomaGideon Bollag, K. B. Nolop, Jeffrey A. Sosman et al.|Nature|2010Cited by 1.8k
RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAFPoulikos I. Poulikakos, Neal Rosen, Chao Zhang et al.|Nature|2010Cited by 1.8k
Structural Bioinformatics-Based Design of Selective, Irreversible Kinase InhibitorsMichael S. Cohen, Jack Taunton, Chao Zhang et al.|Science|2005Cited by 508
Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in ToxoplasmaSebastian Lourido, L. David Sibley, Joel L. Shuman et al.|Nature|2010Cited by 348
Chemical Genetic Analysis of the Time Course of Signal Transduction by JNKJuan‐José Ventura, Roger J. Davis, Anette Hübner et al.|Molecular Cell|2006Cited by 327