Centre National de la Recherche Scientifique
ORCID: 0000-0002-1804-8374Publishes on Cultural Heritage Materials Analysis, Medieval European Literature and History, Building materials and conservation. 495 papers and 11.9k citations.
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Staphylococcus aureus RNAIII is one of the main intracellular effectors of the quorum-sensing system. It is a multifunctional RNA that encodes a small peptide, and its noncoding parts act as antisense RNAs to regulate the translation and/or the stability of mRNAs encoding transcriptional regulators, major virulence factors, and cell wall metabolism enzymes. In this review, we explain how regulatory proteins and RNAIII are embedded in complex regulatory circuits to express virulence factors in a dynamic and timely manner in response to stress and environmental and metabolic changes.