PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical modelsKeith Dredge, Ian Bytheway, Edward Hammond et al.|British Journal of Cancer|2011Cited by 165
The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapyKeith Dredge, Ian Bytheway, Edward Hammond et al.|Investigational New Drugs|2009Cited by 118
Synthesis and Biological Evaluation of Polysulfated Oligosaccharide Glycosides as Inhibitors of Angiogenesis and Tumor GrowthKen D. Johnstone, Vito Ferro, Tomislav Karoli et al.|Journal of Medicinal Chemistry|2010Cited by 72
Abstract A17: The dual angiogenesis/heparanase inhibitor PG545 inhibits solid tumor progression in models of breast, prostate and liver cancer: A comparative assessment of once versus twice weekly administration schedulesEdward Hammond, Keith Dredge, Ian Bytheway et al.|Molecular Cancer Therapeutics|2009Cited by 3