PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical modelsKeith Dredge, Ian Bytheway, Edward Hammond et al.|British Journal of Cancer|2011Cited by 165
The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapyKeith Dredge, Ian Bytheway, Edward Hammond et al.|Investigational New Drugs|2009Cited by 118
Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike–ACE2 InteractionScott E. Guimond, Jeremy E. Turnbull, Alberto A. Amarilla et al.|ACS Central Science|2022Cited by 112
Synthesis and Biological Evaluation of Polysulfated Oligosaccharide Glycosides as Inhibitors of Angiogenesis and Tumor GrowthKen D. Johnstone, Vito Ferro, Tomislav Karoli et al.|Journal of Medicinal Chemistry|2010Cited by 72
Pixatimod (PG545), a clinical-stage heparan sulfate mimetic, is a potent inhibitor of the SARS-CoV-2 virusScott E. Guimond, Jeremy E. Turnbull, Courtney J. Mycroft‐West et al.|Unknown|2020Cited by 16