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Peptidomimetic nitrile inhibitors of malarial protease falcipain-2 with high selectivity against human cathepsinsEmanuela Nizi, Steven J. Harper, Alessio Sferrazza et al.|Bioorganic & Medicinal Chemistry Letters|2018Cited by 25
Gametocyte-specific and all-blood-stage transmission-blocking chemotypes discovered from high throughput screening on Plasmodium falciparum gametocytesGiacomo Paonessa, Pietro Alano, Giulia Siciliano et al.|Communications Biology|2022Cited by 14
Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitroFederica Ferrigno, Jesus M. Ontoria, Ilaria Biancofiore et al.|Bioorganic & Medicinal Chemistry Letters|2018Cited by 5
An allosteric inhibitor of the Zika virus NS2B-NS3 protease with oral efficacy in mouse modelsJesus M. Ontoria, Giacomo Paonessa, Esther Torrente et al.|Nature Communications|2026Cited by 3