Marc Therrien

Institute for Research in Immunology and Cancer

ORCID: 0000-0003-2047-7650

Publishes on Melanoma and MAPK Pathways, Protein Kinase Regulation and GTPase Signaling, Neurobiology and Insect Physiology Research. 75 papers and 8k citations.

PubIndex Score97Top 3%How it's scored

75Publications

8kTotal Citations

First publication: 1991First senior author: 2002

Melanoma and MAPK Pathways Protein Kinase Regulation and GTPase Signaling Neurobiology and Insect Physiology Research Ubiquitin and proteasome pathways Protein Tyrosine Phosphatases

Top publicationsby citations

ERK signalling: a master regulator of cell behaviour, life and fate

Hugo Lavoie, Marc Therrien, Jessica K. Gagnon|Nature Reviews Molecular Cell Biology|2020

Cited by 1.2k

Regulation of RAF protein kinases in ERK signalling

Hugo Lavoie, Marc Therrien|Nature Reviews Molecular Cell Biology|2015

Cited by 701

Inhibition of RAS function through targeting an allosteric regulatory site

Russell Spencer-Smith, John P. O’Bryan, Shohei Koide et al.|Nature Chemical Biology|2016

Cited by 299

Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization

Hugo Lavoie, Marc Therrien, Neroshan Thevakumaran et al.|Nature Chemical Biology|2013

Cited by 178

Crystal structure of a BRAF kinase domain monomer explains basis for allosteric regulation

Neroshan Thevakumaran, Marc Therrien, Hugo Lavoie et al.|Nature Structural & Molecular Biology|2014

Cited by 163