Tau Reduction Prevents Key Features of Autism in Mouse ModelsChao Tai, Lennart Mucke, Che-Wei Chang et al.|Neuron|2020Cited by 105
Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchronyChe-Wei Chang, Lennart Mucke, Mark D. Evans et al.|Cell Reports|2021Cited by 86
Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer’s disease mutations but not by inhibition of BACE1Erik C. B. Johnson, Lennart Mucke, Xinxing Yu et al.|Molecular Neurodegeneration|2020Cited by 76
TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome modelQiang Shao, Lennart Mucke, Che-Wei Chang et al.|Science Translational Medicine|2022Cited by 54
Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse modelsMelanie Das, Lennart Mucke, Wenjie Mao et al.|Neurobiology of Disease|2023Cited by 40