Inactivation of the DNA-Repair Gene<i>MGMT</i>and the Clinical Response of Gliomas to Alkylating AgentsManel Esteller, James G. Herman|New England Journal of Medicine|2000Cited by 2.2k
Incidence and functional consequences of <i>hMLH1</i> promoter hypermethylation in colorectal carcinomaJames G. Herman, Stephen B. Baylin, Asad Umar et al.|Proceedings of the National Academy of Sciences|1998Cited by 1.9k
Correlation of O<sup>6</sup>-Methylguanine Methyltransferase (MGMT) Promoter Methylation With Clinical Outcomes in Glioblastoma and Clinical Strategies to Modulate MGMT ActivityMonika E. Hegi, Mark R. Gilbert, Lili Liu et al.|Journal of Clinical Oncology|2008Cited by 805
SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activityHirohide Yoshikawa, James G. Herman, Kenichi Matsubara et al.|Nature Genetics|2001Cited by 734
Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis.Manel Esteller, James G. Herman, Rosa Ana Risques et al.|PubMed|2001Cited by 323