Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis.

Manel Esteller(Institució Catalana de Recerca i Estudis Avançats), James G. Herman(UPMC Hillman Cancer Center), Rosa Ana Risques(University of Washington), Gabriel Capellá(Institut Català d'Oncologia), Miguel A. Peinado(Badalona Serveis Assistencials), Vı́ctor Moreno(Ajuntament de L’Hospitalet), Stephen B. Baylin(Johns Hopkins University), M Toyota
PubMed
June 15, 2001
Cited by 323


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