Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading ExoribonucleaseMaria L. Agostini, Mark R. Denison, Erica L. Andres et al.|mBio|2018Cited by 1.5k
Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in MiceAndrea J. Pruijssers, Timothy P. Sheahan, Maria L. Agostini et al.|Cell Reports|2020Cited by 541
Biochemical characterization of tirabrutinib and other irreversible inhibitors of Bruton's tyrosine kinase reveals differences in on - and off - target inhibitionAlbert Liclican, Joy Y. Feng, Loredana Serafini et al.|Biochimica et Biophysica Acta (BBA) - General Subjects|2020Cited by 93
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in miceAlexandra Schäfer, Timothy P. Sheahan, David R. Martinez et al.|Science Translational Medicine|2022Cited by 83
Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green MonkeysRichard L. Mackman, Tomáš Cihlář, Rao Kalla et al.|Journal of Medicinal Chemistry|2023Cited by 63