Microbubble-enhanced transcranial focused ultrasound with temozolomide for patients with high-grade glioma (BT008NA): a multicentre, open-label, phase 1/2 trial

Graeme F. Woodworth(West Virginia University), Nir Lipsman(Sunnybrook Health Science Centre), Howard M. Eisenberg(University of Maryland, Baltimore), Arjun Sahgal(Sunnybrook Health Science Centre), Jakob V. E. Gerstl(Brigham and Women's Hospital), Alexandra J. Golby(Brigham and Women's Hospital), Timothy R. Smith(Brigham and Women's Hospital), Maheleth Llinas(Sunnybrook Health Science Centre), Christopher P. Cifarelli(West Virginia University), Christopher Douville(Johns Hopkins University), Chixiang Chen(University of Maryland, Baltimore), Haoyu Ren(Siemens (Germany)), Rania A. Mekary(Brigham and Women's Hospital), Adomas Bunevičius(University of North Carolina at Chapel Hill), Jason P. Sheehan(University of Virginia), Agessandro Abrahão(Sunnybrook Health Science Centre), Harshit Arora(University of Kentucky), Ali R. Rezai(West Virginia University), Dheeraj Gandhi(University of Maryland, Baltimore), Jeffrey Carpenter(West Virginia University), Pavlos Anastasiadis(University of Maryland, Baltimore), Chris Heyn(Sunnybrook Health Science Centre), Anna Ball(Brigham and Women's Hospital), Zhiyuan Xu(Zhejiang Cancer Hospital), Christopher B. Pople(Sunnybrook Health Science Centre), Haroon Ahmad(University of Maryland, Baltimore), Kullervo Hynynen(University of Toronto), Ying Meng(Sunnybrook Health Science Centre), Jeremi Chabros(University of Cambridge), James Perry, Chetan Bettegowda(Johns Hopkins University), Lily C Pham(University of Maryland, Baltimore), Mary Jane Lim-Fat(Sunnybrook Health Science Centre), Cynthia Hawkins(Sunnybrook Health Science Centre), Nathan J. McDannold(Brigham and Women's Hospital), Erickson Torio(Brigham and Women's Hospital), Mary Beth Anketell(Brigham and Women's Hospital), Ahmad Ozair(King George's Medical University)
The Lancet Oncology
November 25, 2025
Cited by 18


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