Pathobiology of the autophagy-lysosomal pathway in the Huntington’s disease brain

Martin J. Berg(Nathan Kline Institute for Psychiatric Research), Ralph A. Nixon(Nathan Kline Institute for Psychiatric Research)

Acta Neuropathologica Communications

November 7, 2025

10.1186/s40478-025-02131-8

Cited by 1

Related Papers

Alzheimer disease

|Nature Reviews Disease Primers|2021|2.4k

Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease

|Journal of Neuroscience|2008|1.1k

Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome

|American Journal Of Pathology|2000|850

Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques

|Nature Neuroscience|2022|606

Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy

|Journal of Neuroscience|2011|466