Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques
Ju‐Hyun Lee(Nathan Kline Institute for Psychiatric Research), Ralph A. Nixon(Nathan Kline Institute for Psychiatric Research)
Cited by 606
Related Papers
Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
|Journal of Neuroscience|2008|1.1k
Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome
|American Journal Of Pathology|2000|847
Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy
|Journal of Neuroscience|2011|466
Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases
|Nature Reviews Molecular Cell Biology|2024|275