Site-Directed Mutagenesis and Time-Resolved Fluorescence Spectroscopy Reveal That Two Hydrogen-Bonded Carboxylic Side Chains Are Essential for GPR68 Proton Sensing and G Protein Binding
B.M. Kapur(Boehringer Ingelheim (Germany)), Gisela Schnapp(Boehringer Ingelheim (Germany)), Ana‐Nicoleta Bondar(Forschungszentrum Jülich), Eva M. Garrido‐Martín(Boehringer Ingelheim (Germany)), Herbert Nar(Boehringer Ingelheim (Germany)), Esther Schmidt(European Bioinformatics Institute), Michael Schuler(Boehringer Ingelheim (Germany))
Cited by 0
Related Papers
Patterns of somatic mutation in human cancer genomes
|Nature|2007|3.1k
Crystal structure analysis of oxidized Pseudomonas aeruginosa azurin at pH 5·5 and pH 9·0
|Journal of Molecular Biology|1991|487
Structure-Based Design of Novel Potent Nonpeptide Thrombin Inhibitors
|Journal of Medicinal Chemistry|2002|454
Biophysics in drug discovery: impact, challenges and opportunities
|Nature Reviews Drug Discovery|2016|383