Advancements and challenges in stem cell transplantation for regenerative medicine

Lingxi Wei(Shanxi Medical University), Wenqi Yan(Shandong University), Wahid Shah(Shanxi Medical University), Zhengwei Zhang(Jiangnan University), Minghe Wang(Shanxi Medical University), Biao Liu(Shanxi Medical University), Zhaoxia Xue(Shanxi Medical University), Yixin Cao(Shanxi Medical University), Xinyu Hou(Hebei Normal University), Kai Zhang(Shanxi Medical University), Beibei Yan(Shanxi Medical University), Xiaogang Wang(Shanxi Medical University)
Heliyon
August 1, 2024
Cited by 64Open Access
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Abstract

Stem cell transplantation has emerged as a promising avenue in regenerative medicine, potentially facilitating tissue repair in degenerative diseases and injuries. This review comprehensively examines recent developments and challenges in stem cell transplantation. It explores the identification and isolation of various stem cell types, including embryonic, induced pluripotent, and adult stem cells derived from multiple sources. Additionally, the review highlights the tissue-specific applications of these stem cells, focusing on bone and cartilage regeneration, treatment of neurological disorders, and management of hematological conditions. Future advancements and effective resolution of current challenges will be crucial in fully realizing the potential of stem cell transplantation in regenerative medicine. With responsible and ethical practices, the field can potentially transform disease and injury treatment, ultimately improving the quality of life for countless individuals.


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