Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection
Martin Jinye Zhang(Broad Institute), Shamil Sunyaev(Harvard University), Steven Gazal(University of Southern California), Po‐Ru Loh(Broad Institute), Arun Durvasula(Broad Institute), Benjamin J. Strober(Harvard University), Huwenbo Shi(SIB Swiss Institute of Bioinformatics), Colby Chiang(Massachusetts General Hospital), Alkes L. Price(Broad Institute), Evan Koch(Brigham and Women's Hospital), Armin Schoech(Broad Institute), Alison R. Barton(Harvard University), Samuel S. Kim(Harvard University), Omer Weissbrod(Harvard University)
Cited by 2
Related Papers
Biological insights from 108 schizophrenia-associated genetic loci
|Nature|2014|8.1k
A second generation human haplotype map of over 3.1 million SNPs
|Nature|2007|4.6k
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
|The American Journal of Human Genetics|2015|1.5k
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
|Nature Communications|2018|1.2k