Biological insights from 108 schizophrenia-associated genetic loci
Jacqueline I. Goldstein(Broad Institute), Phil Lee(Broad Institute), Stephan Ripke(Broad Institute), Hailiang Huang(Broad Institute), Kai-How Farh(Harvard University Press), Mark J. Daly(Broad Institute), Benjamin M. Neale(Broad Institute), Brendan Bulik‐Sullivan(Broad Institute), Menachem Fromer(Broad Institute), Kimberly D. Chambert(Broad Institute), Giulio Genovese(Broad Institute), Jordan W. Smoller(Broad Institute), Phil Lee(Broad Institute), Edward M. Scolnick(Broad Institute), Stephan Ripke(Broad Institute), Elizabeth Bevilacqua(Broad Institute), Jennifer L. Moran(Broad Institute), Aarno Palotie(Broad Institute), Tracey L. Petryshen(Broad Institute), Richard A. Belliveau(Broad Institute), Steven A. McCarroll(Broad Institute), Sarah E. Bergen(Broad Institute), Mark J. Daly(Broad Institute), Benjamin M. Neale(Broad Institute), Brendan Bulik-Sullivan(Broad Institute), Colm O’Dushlaine(Broad Institute), Menachem Fromer(Broad Institute), Eli A. Stahl(Broad Institute), Jacqueline I. Goldstein(Broad Institute), Tõnu Esko (Broad Institute), Benjamin M. Neale(Broad Institute), Tune H. Pers(Broad Institute), Hailiang Huang(Broad Institute), Joel N. Hirschhorn(Broad Institute), Alkes L. Price(Broad Institute), Mark J. Daly(Broad Institute), Phil Lee(Broad Institute), Menachem Fromer(Broad Institute), Benjamin M. Neale(Broad Institute), Jordan W. Smoller(Broad Institute), Aarno Palotie(Broad Institute), Paul Cormican(Trinity College Dublin), Aiden Corvin(Washington University in St. Louis), Michael Gill(Trinity College Dublin), Gary Donohoe(Ollscoil na Gaillimhe – University of Galway), Derek W. Morris (Ollscoil na Gaillimhe – University of Galway), Alexander Richards(Cardiff University), Douglas M. Ruderfer(University of North Carolina at Chapel Hill), Michael J. Owen(Queen Mary University of London), Noa Carrera(Cardiff University), Marian L. Hamshere(Cardiff University), Nick Craddock(University of Bonn), David Kavanagh(University of Antwerp), Michael C. O’Donovan(Lundbeck (Denmark)), Peter Holmans(National and Kapodistrian University of Athens), George Kirov(University College Cork), Sophie E. Legge(University of Oslo), Valentina Escott‐Price(Ollscoil na Gaillimhe – University of Galway), Nigel Williams(Cardiff University), Andrew Pocklington(University of Chicago), Lyudmila Georgieva(University of London), James Walters(Cardiff University), Nick Craddock(University of Regensburg), Michael C. O’Donovan(University of Helsinki), Michael J. Owen(Cardiff University), Peter Holmans(Cardiff University), David Collier(Eli Lilly (United States)), Younes Mokrab(University of North Carolina at Chapel Hill), David Collier(Eli Lilly (United States)), Tune H. Pers(Broad Institute), Tõnu Esko(Broad Institute), Tune H. Pers(Broad Institute), Joel N. Hirschhorn (Broad Institute), Erik Söderman(Karolinska Institutet), Ingrid Agartz(Broad Institute), Erik G. Jönsson(Broad Institute), Ingrid Agartz(University of Oslo), Srdjan Djurovic(Oslo University Hospital), Morten Mattingsdal(University of North Carolina at Chapel Hill), Ingrid Agartz(University of Oslo), Ole A. Andreassen(Broad Institute), Erik G. Jönsson(Russian Academy of Sciences), Ingrid Melle(Oslo University Hospital), Esben Agerbo(The University of Queensland), Preben Bo Mortensen(Aarhus University), Esben Agerbo(Max Planck Society), Preben Bo Mortensen(Aarhus University), Preben Bo Mortensen(Illumina (United States)), Anders D. Børglum(Lundbeck (Denmark)), Henrik B. Rasmussen(Mental Health Services), Ditte Demontis(Aarhus University), Esben Agerbo(Aarhus University), Line Olsen(University of Bonn), Manuel Mattheisen(Broad Institute), Ole Mors(University of Bonn), Thomas Werge(University of Copenhagen), Thomas Folkmann Hansen(Statens Serum Institut), Margot Albus(Statens Serum Institut), Madeline Alexander(Fujita Health University), Claudine Laurent(Sorbonne Université), Douglas F. Levinson(Universitat Autònoma de Barcelona), Farooq Amin(Emory University), Farooq Amin(Emory University), Silviu‐Alin Bacanu(Virginia Commonwealth University), Bradley T. Webb(University of Groningen), Tim B. Bigdeli(Virginia Commonwealth University), Brandon Wormley(Virginia Commonwealth University), Christian Hammer(University of Toronto), Martin Begemann(Max Planck Institute of Experimental Medicine), Sergi Papiol(University of North Carolina at Chapel Hill), Hannelore Ehrenreich(Latvian Biomedical Research and Study Centre), Judit Bene (University of Southern California), Béla Melegh(Martin Luther University Halle-Wittenberg), Judit Bene (Vilnius University), Béla Melegh(Vilnius University), Christina M. Hultman(Charles University), Patrik K. E. Magnusson(Karolinska Institutet), Patrick F. Sullivan(University of North Carolina at Chapel Hill), Anna K. Kähler(National University of Singapore), Sarah E. Bergen(Broad Institute), Donald W. Black(University of Iowa), Richard Bruggeman(University Medical Center Groningen), Nancy G. Buccola(Louisiana State University Health Sciences Center New Orleans), Joshua L. Roffman(Sichuan University), Randy L. Buckner(Harvard University), Randy L. Buckner(Harvard University), Joshua L. Roffman(Massachusetts General Hospital), Randy L. Buckner(Harvard University), William Byerley(University of California, San Francisco), Roel A. Ophoff(University of California, Los Angeles), René S. Kahn(Charles University), Wiepke Cahn(Karolinska Institutet), Eric Strengman(Johns Hopkins University), Joseph D. Buxbaum(Allen Institute for Brain Science), Guiqing Cai(Université Paris Cité), Jeremy M. Silverman(Universitat Autònoma de Barcelona), Vahram Haroutunian(Allen Institute for Brain Science), Joseph D. Buxbaum(Allen Institute for Brain Science), Elena Parkhomenko(Harvard University Press), Joseph I. Friedman(Ollscoil na Gaillimhe – University of Galway), Elodie Drapeau(University of Edinburgh), Guiqing Cai(Heidelberg University), Kenneth L. Davis(Amsterdam University of the Arts), Abraham Reichenberg(University of Pecs), Dominique Campion(Inserm), Roel A. Ophoff(University of California, Los Angeles), Rita M. Cantor(University of California, Los Angeles), Frans Henskens(Schizophrenia Research Institute), Vaughan J. Carr(UNSW Sydney), Christos Pantelis(Medical University of Sofia), Carmel M. Loughland(Eli Lilly (United States)), Patricia T. Michie(Ollscoil na Gaillimhe – University of Galway), Assen V. Jablensky(Lundbeck (Denmark)), Rodney J. Scott(Royal College of Surgeons in Ireland), Stanley V. Catts(King's College London), Ulrich Schall(Maastricht University), Vaughan J. Carr(Max Planck Society), Stanley V. Catts(Royal Brisbane and Women's Hospital), Raymond Chan(Institute of Psychology, Chinese Academy of Sciences), Hon‐Cheong So(The University of Queensland), Ronald Y.L. Chen(Johns Hopkins University), Pak C. Sham(Chinese University of Hong Kong), Emily Wong(Latvian Biomedical Research and Study Centre), Eric Chen(Eli Lilly (United States)), Miaoxin Li(Chinese University of Hong Kong), Miaoxin Li (Chinese University of Hong Kong), Eric Chen(Broad Institute), Pak C. Sham(Queen's University Belfast), Wei Cheng(University of North Carolina at Chapel Hill), Eric Cheung(Castle Peak Hospital), Jimmy Lee(Lundbeck (Denmark)), Siow Ann Chong(King's College London), Kang Sim(The University of Melbourne), Mythily Subramaniam(National and Kapodistrian University of Athens), C. Robert Cloninger(Max Planck Society), Dragan M. Švrakić(Washington University in St. Louis), David Cohen(University of Southern California), Nadine Cohen(University of Helsinki), Yunjung Kim(University of North Carolina at Chapel Hill), Stephanie Williams(University of North Carolina at Chapel Hill), Martilias S. Farrell(University of North Carolina at Chapel Hill), James J. Crowley(University of North Carolina at Chapel Hill), Paola Giusti‐Rodríguez(University of North Carolina at Chapel Hill), Patrick F. Sullivan(University of North Carolina at Chapel Hill), Jin Szatkiewicz(Broad Institute), David Curtis(Johns Hopkins University), David Curtis(Queen Mary University of London), Jonathan Pimm(University of Oxford), Andrew McQuillin(Lundbeck (Denmark)), Hugh Gurling(University College London), Michael Davidson(Virginia Commonwealth University), Mark Weiser(Sheba Medical Center), Sven Cichon (University of Bonn), Franziska Degenhardt(University of Bonn), Andrea Hofman(University of Bonn), Per Hoffmann(University of Bonn), Markus M. Nöthen(University of Bonn), Stefan Herms(University of Bonn), Sven Cichon(University of Bonn), Franziska Degenhardt(University of Bonn), Andrea Hofman(University of Bonn), Per Hoffmann(Broad Institute), Markus M. Nöthen(University of Bonn), Stefan Herms(University of Bonn), Jurgen Del‐Favero(National Institutes of Health), Anders D. Børglum(University of Iceland), Manuel Mattheisen(University of Bonn), Ole Mors(Aarhus University), Ditte Demontis(Aarhus University), Anders D. Børglum(Aarhus University), Manuel Mattheisen (Broad Institute), Ditte Demontis(Aarhus University), George N. Papadimitriou(University of Oxford), Dimitris Dikeos(Broad Institute), Timothy G. Dinan(deCODE Genetics (Iceland)), Srdjan Djurovic(Oslo University Hospital), Gary Donohoe(Ollscoil na Gaillimhe – University of Galway), Derek W. Morris(Ollscoil na Gaillimhe – University of Galway), Jubao Duan(NorthShore University HealthSystem), Alan R. Sanders (NorthShore University HealthSystem), Pablo V. Gejman(NorthShore University HealthSystem), Jubao Duan(NorthShore University HealthSystem), Alan R. Sanders (NorthShore University HealthSystem), Pablo V. Gejman(NorthShore University HealthSystem), Frank Dudbridge(University of North Carolina at Chapel Hill), Naser Durmishi(Karolinska Institutet), Peter Eichhammer(University of Regensburg), Johan G. Eriksson(Helsinki University Hospital), Johan G. Eriksson(University of Verona), Veikko Salomaa(Finnish Institute for Health and Welfare), Johan G. Eriksson(Royal College of Surgeons in Ireland), Laurent Essioux(Roche (Switzerland)), Ayman H. Fanous(University of Southern California), Ayman H. Fanous(University of Southern California), Ayman H. Fanous(University of Southern California), Ayman H. Fanous(University of Southern California), Thomas G. Schulze(The University of Western Australia), Stephanie H. Witt(Heidelberg University), Jana Strohmaier(University of North Carolina at Chapel Hill), Sandra Meier(Heidelberg University), Josef Frank(Virginia Commonwealth University), Marcella Rietschel(Heidelberg University), Lude Franke(University Medical Center Groningen), Juha Karjalainen(University Medical Center Groningen), Ann Olincy(University of Toronto), Robert Freedman(Agency for Science, Technology and Research), Nelson B. Freimer(University of California, Los Angeles), Roel A. Ophoff(University of California, Los Angeles), Marion Friedl(deCODE Genetics (Iceland)), Ina Giegling(The University of Queensland), Bettina Konte(University Hospital in Halle), Annette M. Hartmann(University of Oslo), Dan Rujescu(Munich University of Applied Sciences), Douglas M. Ruderfer(University College London), Eli A. Stahl (Broad Institute), Pamela Sklar(Allen Institute for Brain Science), Menachem Fromer(Broad Institute), Shaun Purcell(Hebrew University of Jerusalem), Panos Roussos(Icahn School of Medicine at Mount Sinai), Dan Rujescu(Max Planck Society), Ina Giegling (Broad Institute), Stephanie Godard(Inserm), В. Е. Голимбет(Trinity College Dublin), Qingqin S. Li(Janssen (United States)), Srihari Gopal(Karolinska Institutet), Dai Wang(Fujita Health University), Naomi R. Wray(The University of Queensland), Bryan Mowry(The University of Queensland), Peter M. Visscher(The University of Queensland), Jacob Gratten(The University of Queensland), Sang Lee(The University of Queensland), Lieuwe de Haan(Northwell Health), Carin J. Meijer(Amsterdam UMC Location University of Amsterdam), Mark Hansen(Janssen (Belgium)), Thomas Folkmann Hansen(Agency for Science, Technology and Research), Line Olsen(Northwell Health), Henrik B. Rasmussen(Broad Institute), Thomas Werge(University of Copenhagen), Vahram Haroutunian(Broad Institute), Pamela Sklar(Allen Institute for Brain Science), Joseph D. Buxbaum (Allen Institute for Brain Science), Vahram Haroutunian(Allen Institute for Brain Science), Frans Henskens(University of California, Los Angeles), Frans Henskens(Schizophrenia Research Institute), Stefan Herms(Broad Institute), Per Hoffmann(University of Southern California), Sven Cichon(Broad Institute), Steven A. McCarroll(Broad Institute), Tõnu Esko(Broad Institute), Joel N. Hirschhorn(Broad Institute), David M. Hougaard(Statens Serum Institut), Mads V. Hollegaard(Statens Serum Institut), Masashi Ikeda(Fujita Health University), Nakao Iwata(Fujita Health University), Inge Joa(Johns Hopkins University), Sara Marsal(Pfizer (United States)), Antonio Julià(University of Copenhagen), Luba Kalaydjieva(Broad Institute), Luba Kalaydjieva(University of North Carolina at Chapel Hill), Assen V. Jablensky(The University of Western Australia), Драга Тончева(Medical University of Sofia), Sena Karachanak-Yankova(Medical University of Sofia), Matthew C. Keller(University of Colorado Boulder), Clement C. Zai(Centre for Addiction and Mental Health), Jo Knight(Centre for Addiction and Mental Health), James L. Kennedy(Centre for Addiction and Mental Health), Clement C. Zai(Centre for Addiction and Mental Health), Jo Knight(Centre for Addiction and Mental Health), James L. Kennedy(Centre for Addiction and Mental Health), James L. Kennedy(Centre for Addiction and Mental Health), Jo Knight(Centre for Addiction and Mental Health), P. A. Slominsky(Institute of Molecular Genetics), Limborskaia Sa(Institute of Molecular Genetics), Andrey Khrunin(Institute of Molecular Genetics), Jānis Kloviņš(Latvian Biomedical Research and Study Centre), Liene Ņikitina-Zaķe(Latvian Biomedical Research and Study Centre), Carlos N. Pato(University of Southern California), Michele T. Pato(University of Southern California), James A. Knowles(University of Southern California), Vaidutis Kučinskas(Vilnius University), Zita Aušrelė Kučinskienė(Vilnius University), Hana Kuzelova-Ptackova(University Hospital in Motol), Milan Maçek(University Hospital in Motol), Claudine Laurent(Sorbonne Université), Jimmy Lee(Duke-NUS Medical School), Bernard Lerer(Hadassah Medical Center), Pak C. Sham(Chinese University of Hong Kong), Miaoxin Li (Chinese University of Hong Kong), Qiang Wang(Sichuan University), Tao Li(Sichuan University), Kung‐Yee Liang(Johns Hopkins University), T. Scott Stroup(Columbia University), Jeffrey A. Lieberman(Columbia University), Carmel M. Loughland (Schizophrenia Research Institute), Ulrich Schall(Schizophrenia Research Institute), Jan Lubiński(International Hereditary Cancer Center), Jouko Lönnqvist(Finnish Institute for Health and Welfare), Jaana Suvisaari(Finnish Institute for Health and Welfare), Jouko Lönnqvist(Finnish Institute for Health and Welfare), Jaana Suvisaari(Finnish Institute for Health and Welfare), Brion S. Maher(Johns Hopkins University), Wolfgang Maier(University of Bonn), Jacques Mallet(Laboratoire de Microbiologie et Génétique Moléculaires), Manuel Mattheisen(University of Bonn), Morten Mattingsdal(University of Oslo), Larry J. Seidman (Beth Israel Deaconess Medical Center), Raquelle I. Mesholam-Gately(Beth Israel Deaconess Medical Center), Robert W. McCarley(Harvard University), Tracey L. Petryshen(Broad Institute), Robert W. McCarley(Harvard University), Colm McDonald(Ollscoil na Gaillimhe – University of Galway), Andrew M. McIntosh(Alzheimer Scotland), Douglas H. R. Blackwood(University of Edinburgh), Andrew M. McIntosh(Alzheimer Scotland), Ole A. Andreassen(Oslo University Hospital), Ingrid Melle(Oslo University Hospital), Raquelle I. Mesholam-Gately (Beth Israel Deaconess Medical Center), Larry J. Seidman(Beth Israel Deaconess Medical Center), Mari Nelis(Estonian Biocentre), Andres Metspalu(Estonian Biocentre), Lili Milani(Estonian Biocentre), Tõnu Esko(Broad Institute), Patricia T. Michie(Schizophrenia Research Institute), Vihra Milanova(Medical University of Sofia), Ole Mors (Aarhus University), Anders D. Børglum(Aarhus University), Kieran C. Murphy(Royal College of Surgeons in Ireland), Robin Murray(King's College London), John Powell(King's College London), Inez Myin‐Germeys(Maastricht University Medical Centre), Jim van Os(King's College London), Bertram Müller-Myhsok(University of Liverpool), Bertram Müller-Myhsok(University of Liverpool), Bertram Müller-Myhsok(University of Liverpool), Igor Nenadić(Jena University Hospital), Deborah A. Nertney(The University of Queensland), Gerald Nestadt(Johns Hopkins University), Ann E. Pulver(Johns Hopkins University), Kristin K. Nicodemus(Trinity College Dublin), Laura Nisenbaum(Eli Lilly (United States)), Annelie Nordin(Umeå University), Rolf Adolfsson(Umeå University), Eadbhard O’Callaghan(Data Fusion International (Ireland)), F. Anthony O’Neill(Queen's University Belfast), Sang‐Yun Oh(Lawrence Berkeley National Laboratory), Jim van Os(King's College London), Christos Pantelis(Melbourne Health), Tiina Paunio(University of Helsinki), Tiina Paunio(University of Helsinki), Olli Pietiläinen(Finnish Institute for Health and Welfare), Milica Pejović-Milovančević(University of Belgrade), Diana O. Perkins(University of North Carolina at Chapel Hill), Patrick F. Sullivan(University of North Carolina at Chapel Hill), Olli Pietiläinen (Finnish Institute for Health and Welfare), Aarno Palotie(Broad Institute), Alkes L. Price(Broad Institute), Digby Quested(University of Oxford), Mark A. Reimers(Virginia Commonwealth University), Aaron R. Wolen(Virginia Commonwealth University), Pamela Sklar(Allen Institute for Brain Science), Panos Roussos (Icahn School of Medicine at Mount Sinai), Jens R. Wendland(Pfizer (United States)), Christian Schubert(Pfizer (United States)), Thomas G. Schulze(Heidelberg University), Sibylle G. Schwab(Universitätsklinikum Erlangen), Rodney J. Scott(Hunter New England Local Health District), Rodney J. Scott(Hunter New England Local Health District), Jianxin Shi(National Cancer Institute), Engilbert Sigurðsson(National University Hospital of Iceland), Teimuraz Silagadze(Tbilisi State Medical University), Jeremy M. Silverman(Veterans Health Administration), ChrisC. A. Spencer(Centre for Human Genetics), Hreinn Stefánsson(deCODE Genetics (Iceland)), Kari Stefansson(deCODE Genetics (Iceland)), Stacy Steinberg(deCODE Genetics (Iceland)), Elisabeth Stögmann(Medical University of Vienna), Fritz Zimprich(Medical University of Vienna), D.R. Weinberger(Johns Hopkins University), Richard E. Straub(Lieber Institute for Brain Development), Eric Strengman(University Medical Center Utrecht), Srinivas Thirumalai(Berkshire Healthcare NHS Foundation Trust), Sarah Tosato(University of Verona), Juha Veijola(Oulu University Hospital), Juha Veijola(Oulu University Hospital), Dermot Walsh(Health Research Board), Dieter B. Wildenauer(The University of Western Australia), Assen V. Jablensky(The University of Western Australia), Hualin Simon Xi(Pfizer (United States)), Jianjun Liu(National University of Singapore), Joseph D. Buxbaum(Allen Institute for Brain Science), Sven Cichon(University of Bonn), Ariel Darvasi(Hebrew University of Jerusalem), Enrico Domenici(Roche (Switzerland)), Assen Jablensky(The University of Western Australia), Brien P. Riley(Virginia Commonwealth University), Kenneth S. Kendler(Virginia Commonwealth University), Todd Lencz (Feinstein Institute for Medical Research), Anil K. Malhotra(Feinstein Institute for Medical Research), Todd Lencz (Feinstein Institute for Medical Research), Anil K. Malhotra(Feinstein Institute for Medical Research), Todd Lencz (Feinstein Institute for Medical Research), Anil K. Malhotra(Feinstein Institute for Medical Research), Jianjun Liu(National University of Singapore), Bryan Mowry(The University of Queensland), Tracey L. Petryshen(Broad Institute), Daniëlle Posthuma(Erasmus MC), Daniëlle Posthuma(Erasmus MC), Daniëlle Posthuma(Erasmus MC), David St Clair(University of Aberdeen), D.R. Weinberger(Johns Hopkins University), Thomas Werge(University of Copenhagen)
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