Identification and Optimization of RNA-Splicing Modulators as Huntingtin Protein-Lowering Agents for the Treatment of Huntington’s Disease

Longbin Liu(CHDI Foundation), Ignacio Muñoz-Sanjuán(CHDI Foundation), Brett Cosgrove(Charles River Laboratories (Netherlands)), Amanda J. Van de Poël(Charles River Laboratories (Netherlands)), Manuel Daldin(IRBM Science Park), Douglas Macdonald(TAE Technologies, Inc (United States)), Emanuela Gancia(Charles River Laboratories (Netherlands)), Amy O’Neill(Charles River Laboratories (Netherlands)), Vinod Khetarpal(CHDI Foundation), Natsuko Macabuag(Charles River Laboratories (Netherlands)), William Esmieu(Charles River Laboratories (Netherlands)), Alan F. Haughan, Cole Clissold(Charles River Laboratories (Netherlands)), Marta Stebbeds(Charles River Laboratories (Netherlands)), M.G. Chambers(Charles River Laboratories (Netherlands)), Edith Monteagudo(IRBM Science Park), Tammy Ladduwahetty(Charles River Laboratories (Netherlands)), Laure Grand Moursel(Charles River Laboratories (Netherlands)), Steve Clifton(Charles River Laboratories (Netherlands)), Stephen J. Webster(Charles River Laboratories (Netherlands)), Matthew R. Lee(Amgen (United States)), Nikolay V. Plotnikov(CHDI Foundation), Sara Compte-Sancerni(Charles River Laboratories (Netherlands)), Karine Malagu(Charles River Laboratories (Netherlands)), Huw D. Vater(Charles River Laboratories (Netherlands)), Dario Magnani(Charles River Laboratories (Netherlands)), Hiral Patel(Charles River Laboratories (Netherlands)), John E. Mangette(Albany Molecular Research (United States)), Todd Herbst(CHDI Foundation), Marta da Silva(Charles River Laboratories (Netherlands)), Andrew J. Stott, Taneli Heikkinen, Jonathan A. Spencer(Charles River Laboratories (Netherlands)), Daniel Mota‐Rojas(Universidad Autónoma Metropolitana), Alberto Bresciani(University of Bergamo), Ovadia Lazari(Pfizer (United Kingdom)), Valentina Fodale(IRBM Science Park), Daniel Todd(Charles River Laboratories (Netherlands)), Eva Kritikou(Charles River Laboratories (Netherlands)), Mijke Visser(Charles River Laboratories (Netherlands)), Helen C. Atton(Charles River Laboratories (Netherlands)), Philip B. Mitchell(UNSW Sydney), S Bonomo(Charles River Laboratories (Netherlands)), Benjamin Sutton(Charles River Laboratories (Netherlands)), D. Spadafora(IRBM Science Park), Tamuna Bolkvadze, Elizabeth M. Doherty(CHDI Foundation), Perla Breccia, María Eugenia Herva(Unknown), George McAllister
Journal of Medicinal Chemistry
September 15, 2023
Cited by 7


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