Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy

Xiaoying Chen; Maria Firulyova; Melissa Manis; Jasmin Herz; Igor Smirnov; Ekaterina Aladyeva; Chanung Wang; Xin Bao; Mary Beth Finn; Hao Hu; Irina Shchukina; Min Woo Kim; Carla M. Yuede; Jonathan Kipnis; Maxim N. Artyomov; Jason D. Ulrich; David M. Holtzman

doi:10.1038/s41586-023-05788-0

Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy

Xiaoying Chen(Hope Center for Neurological Disorders), Maria Firulyova(Federal Almazov North-West Medical Research Centre), Melissa Manis(Hope Center for Neurological Disorders), Jasmin Herz(Washington University in St. Louis), Igor Smirnov(Washington University in St. Louis), Ekaterina Aladyeva(Washington University in St. Louis), Chanung Wang(Hope Center for Neurological Disorders), Xin Bao(Hope Center for Neurological Disorders), Mary Beth Finn(Hope Center for Neurological Disorders), Hao Hu(Hope Center for Neurological Disorders), Irina Shchukina(Washington University in St. Louis), Min Woo Kim(Washington University in St. Louis), Carla M. Yuede(Hope Center for Neurological Disorders), Jonathan Kipnis(Washington University in St. Louis), Maxim N. Artyomov(Washington University in St. Louis), Jason D. Ulrich(Hope Center for Neurological Disorders), David M. Holtzman(Washington University in St. Louis)

Nature

March 8, 2023

10.1038/s41586-023-05788-0

Cited by 588Open Access

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