ABL1/2 and DDR1 Drive MEKi Resistance in NRAS-Mutant Melanomas by Stabilizing RAF/MYC/ETS1 and Promoting RAF Homodimerization

Anastasia Lyon(University of Kentucky), Rina Plattner(University of Kentucky), Saptadwipa Ganguly(University of Kentucky), Sujata Mukherjee(University of Kentucky), Yuanyuan Wu(Third Affiliated Hospital of Zhengzhou University), Daheng He(University of Kentucky), Haining Zhu(University of Arizona), Chi Wang(Markey Cancer Center), Jing Chen, R. P. Tripathi(University of Kentucky), Jinpeng Liu(University of Kentucky), Christina Meeks(University of Kentucky)
Cancers
February 2, 2023
10.3390/cancers15030954
Cited by 3

Related Papers

c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF
|Genes & Development|1999|426
Activation of Abl Tyrosine Kinases Promotes Invasion of Aggressive Breast Cancer Cells
|Cancer Research|2006|199
Imatinib Reverses Doxorubicin Resistance by Affecting Activation of STAT3-Dependent NF-κB and HSP27/p38/AKT Pathways and by Inhibiting ABCB1
|PLoS ONE|2013|133
Molecular cytogenetic analysis of inv dup(15) chromosomes, using probes specific for the Prader-Willi/Angelman syndrome region: clinical implications.
|PubMed|1994|129
Abl tyrosine kinases are required for infection by Shigella flexneri
|The EMBO Journal|2003|125