PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruption
Sophia Ladraa(Inserm), Guillaume Canaud(Université Paris Cité), Patrick Villarèse(Université Paris Cité), Céline Cruciani‐Guglielmacci(Centre National de la Recherche Scientifique), Pacifique Levy(Sorbonne Université), Célia Chapelle(Hôpital Necker-Enfants Malades), Antoine Fraissenon(Université Claude Bernard Lyon 1), Charles Bayard(Inserm), G Morin(Inserm), Pierre Isnard(Hôpital Necker-Enfants Malades), Jessica Denom(Centre National de la Recherche Scientifique), Thomas Viel(Inserm), Laurent Guibaud(Hospices Civils de Lyon), Julie Bruneau(Délégation Paris 5), Ivan Nemazanyy(Centre National de la Recherche Scientifique), Lola Zerbib(Hôpital Necker-Enfants Malades), Christine Broissand(Hôpital Necker-Enfants Malades), Vahid Asnafi(Hôpital Necker-Enfants Malades), Mario Pende(Centre National de la Recherche Scientifique), Gwennhaël Autret(Inserm), Nicolas Goudin(Délégation Paris 5), Julien Dairou(Centre National de la Recherche Scientifique), Christophe Legendre(Hôpital Necker-Enfants Malades), Quitterie Venot(Hôpital Necker-Enfants Malades), Michaël Dussiot(Laboratory of Excellence GR-Ex), Alix Besançon(Hôpital Necker-Enfants Malades), Bertrand Tavitian(Inserm), Alexandre P. Garneau(Inserm), Clément Hoguin(Inserm), Jean‐Marc Lacorte(Sorbonne Université), Sophie Kaltenbach(Assistance Publique – Hôpitaux de Paris), Jean–Paul Duong Van Huyen(Hôpital Necker-Enfants Malades), Michel Polak(Délégation Paris 5), Sylvie Fraitag(Hôpital Necker-Enfants Malades)
Cited by 33
Related Papers
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
|Nature|1998|2.4k
Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1
|Journal of Clinical Investigation|2008|1.8k
Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages
|Blood|2016|1.6k
The Banff 2019 Kidney Meeting Report (I): Updates on and clarification of criteria for T cell– and antibody-mediated rejection
|American Journal of Transplantation|2020|809
The Banff 2015 Kidney Meeting Report: Current Challenges in Rejection Classification and Prospects for Adopting Molecular Pathology
|American Journal of Transplantation|2016|625