Discovery of KRas G12C-IN-3 and Pomalidomide-based PROTACs as degraders of endogenous KRAS G12C with potent anticancer activity

Ling Li(Zhumadian Central Hospital), Yinrong Wu(Southern Medical University), Chenglong Xu(Southern Medical University), Zichao Yang(Southern Medical University), Jingxuan Chen(Guangdong Pharmaceutical University), Huiting Zhao(Shandong University of Technology), Jin Liu(Capital Medical University)
Bioorganic Chemistry
October 22, 2021
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